SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eeh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		4 / 6 LEU A  31
PHE A  27
TYR A  41
VAL A 117
 None
 1.08A 1ibgH-3eehA:
undetectable		 1ibgH-3eehA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		5 / 12 ILE A  37
GLY A 119
ILE A 102
ILE A  23
LEU A  78
 None
None
PG5  A 126 ( 4.4A)
None
None
 0.91A 3uj6A-3eehA:
undetectable		 3uj6A-3eehA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		5 / 12 ILE A  37
GLY A 119
ILE A 102
ILE A  23
LEU A  78
 None
None
PG5  A 126 ( 4.4A)
None
None
 0.89A 3uj7B-3eehA:
undetectable		 3uj7B-3eehA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		4 / 8 TRP A  45
ARG A  47
TYR A  96
GLU A  94
 None
 1.13A 3zmdA-3eehA:
undetectable
3zmdB-3eehA:
undetectable		 3zmdA-3eehA:
23.20
3zmdB-3eehA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		4 / 7 ASP A  58
ASN A  61
ILE A  63
TRP A  45
 None
 1.20A 4ii8A-3eehA:
undetectable		 4ii8A-3eehA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		4 / 6 ARG A  98
GLY A  46
THR A  93
GLU A  94
 None
 0.90A 5ny7A-3eehA:
undetectable		 5ny7A-3eehA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		5 / 10 TYR A  41
ILE A  23
ASN A  61
LEU A  31
LEU A  60
 None
 1.23A 5y7pB-3eehA:
undetectable		 5y7pB-3eehA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE
(Haloarcula
marismortui) 		4 / 7 ALA A 121
GLY A 119
GLY A 104
ASN A  21
 PG5  A 126 ( 4.6A)
None
None
None
 0.78A 5ybbB-3eehA:
undetectable		 5ybbB-3eehA:
13.95