SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eet'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		4 / 4 ARG A 240
GLN A  98
PHE A 139
LEU A 207
 None
 1.05A 3abkC-3eetA:
undetectable		 3abkC-3eetA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		5 / 10 ILE A  37
ALA A  13
LEU A  31
LEU A  55
VAL A  54
 None
 0.90A 3o02A-3eetA:
undetectable
3o02B-3eetA:
undetectable		 3o02A-3eetA:
23.87
3o02B-3eetA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		4 / 5 SER A 111
GLU A 153
THR A 135
TYR A 137
 None
 1.16A 3zs3A-3eetA:
undetectable		 3zs3A-3eetA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		4 / 4 VAL A 190
THR A 191
GLU A 192
GLU A 193
 None
 1.22A 4l78A-3eetA:
undetectable		 4l78A-3eetA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		5 / 9 GLU A  58
LEU A  49
VAL A  12
LEU A  16
ILE A  37
 None
 0.97A 4r38C-3eetA:
undetectable		 4r38C-3eetA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		3 / 3 ARG A 240
PHE A 139
LEU A 207
 None
 0.51A 5x1bC-3eetA:
undetectable		 5x1bC-3eetA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		4 / 8 ALA A 156
THR A 158
THR A 161
ALA A 181
 None
 1.03A 5x2tI-3eetA:
undetectable
5x2tJ-3eetA:
undetectable
5x2tK-3eetA:
undetectable
5x2tL-3eetA:
undetectable		 5x2tI-3eetA:
18.18
5x2tJ-3eetA:
20.22
5x2tK-3eetA:
18.18
5x2tL-3eetA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR
(Streptomyces
avermitilis) 		4 / 5 PRO A 154
VAL A 229
GLY A 173
VAL A 163
 None
 0.96A 6ak3B-3eetA:
undetectable		 6ak3B-3eetA:
17.34