SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3eev CHLORAMPHENICOL
ACETYLTRANSFERASE
(Vibrio
cholerae) 		3 / 3 ILE A 134
ILE A 159
LEU A 172
 None
 0.55A 2prgA-3eevA:
undetectable		 2prgA-3eevA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3eev CHLORAMPHENICOL
ACETYLTRANSFERASE
(Vibrio
cholerae) 		4 / 8 ILE A  58
ILE A 117
ALA A  68
VAL A  17
 None
 0.69A 4jltA-3eevA:
undetectable		 4jltA-3eevA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 3eev CHLORAMPHENICOL
ACETYLTRANSFERASE
(Vibrio
cholerae) 		4 / 6 ALA A 207
SER A 205
SER A 187
PRO A 180
 None
 0.96A 5c6pA-3eevA:
undetectable		 5c6pA-3eevA:
17.61