SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 11 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.47A 2f162-3eexA:
undetectable		 2f162-3eexA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 11 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.47A 2f16N-3eexA:
undetectable		 2f16N-3eexA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 7 SER A 121
LEU A  88
LEU A  99
THR A 115
 None
 0.83A 3cfqA-3eexA:
undetectable
3cfqB-3eexA:
undetectable		 3cfqA-3eexA:
19.43
3cfqB-3eexA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		3 / 3 ARG A 208
ASP A 187
ASP A 210
 None
 0.86A 3jayA-3eexA:
undetectable		 3jayA-3eexA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		3 / 3 ARG A 208
ASP A 187
ASP A 210
 None
 0.80A 3jb2A-3eexA:
undetectable		 3jb2A-3eexA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		3 / 3 ARG A 208
ASP A 187
ASP A 210
 None
 0.84A 3jb3A-3eexA:
undetectable		 3jb3A-3eexA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 12 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.46A 3mg02-3eexA:
undetectable
3mg0V-3eexA:
undetectable		 3mg02-3eexA:
20.96
3mg0V-3eexA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 11 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.45A 3mg0N-3eexA:
undetectable		 3mg0N-3eexA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 7 SER A 121
LEU A  88
LEU A  99
THR A 115
 None
 0.81A 4ikkA-3eexA:
undetectable
4ikkB-3eexA:
undetectable		 4ikkA-3eexA:
19.75
4ikkB-3eexA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 11 LEU A  41
VAL A  42
LEU A  88
GLY A  74
LEU A  34
 None
 1.26A 4zbqA-3eexA:
undetectable		 4zbqA-3eexA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 12 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.48A 5l5zV-3eexA:
undetectable
5l5zb-3eexA:
undetectable		 5l5zV-3eexA:
21.43
5l5zb-3eexA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 241
THR A 245
THR A 246
SER A 224
GLY A 225
 None
 1.26A 5l5zH-3eexA:
undetectable
5l5zN-3eexA:
undetectable		 5l5zH-3eexA:
21.43
5l5zN-3eexA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 241
THR A 245
THR A 246
SER A 224
ALA A 227
 None
 1.31A 5lf3b-3eexA:
undetectable		 5lf3b-3eexA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.23A 5lf3b-3eexA:
undetectable		 5lf3b-3eexA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 241
THR A 245
THR A 246
SER A 224
ALA A 227
 None
 1.30A 5lf3N-3eexA:
undetectable		 5lf3N-3eexA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.24A 5lf3N-3eexA:
undetectable		 5lf3N-3eexA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR A 245
THR A 246
SER A 224
GLY A 225
ALA A 227
 None
 1.21A 5lf7V-3eexA:
undetectable
5lf7b-3eexA:
undetectable		 5lf7V-3eexA:
21.56
5lf7b-3eexA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL A  32
GLY A  74
LEU A  76
THR A  89
 None
 0.98A 5sxqA-3eexA:
undetectable		 5sxqA-3eexA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL A  32
GLY A  74
LEU A  76
THR A  89
 None
 0.99A 5sxtA-3eexA:
undetectable		 5sxtA-3eexA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3eex OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL A  32
GLY A  74
LEU A  76
THR A  89
 None
 0.99A 5sxtB-3eexA:
undetectable		 5sxtB-3eexA:
19.75