SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3efa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 GLU A 131
VAL A 136
ARG A  19
GLU A  62
 None
 1.25A 1s3zA-3efaA:
12.7
1s3zB-3efaA:
12.6		 1s3zA-3efaA:
19.16
1s3zB-3efaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.25A 3jx1A-3efaA:
undetectable
3jx1B-3efaA:
undetectable		 3jx1A-3efaA:
17.09
3jx1B-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.24A 3nlyA-3efaA:
undetectable
3nlyB-3efaA:
undetectable		 3nlyA-3efaA:
17.09
3nlyB-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.24A 3rqlA-3efaA:
undetectable
3rqlB-3efaA:
undetectable		 3rqlA-3efaA:
17.09
3rqlB-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.24A 4capA-3efaA:
undetectable
4capB-3efaA:
undetectable		 4capA-3efaA:
17.09
4capB-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.22A 4d32A-3efaA:
undetectable
4d32B-3efaA:
1.3		 4d32A-3efaA:
17.09
4d32B-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 PHE A  35
SER A  30
ARG A  19
VAL A  24
 None
 1.22A 4v3yA-3efaA:
undetectable
4v3yB-3efaA:
undetectable		 4v3yA-3efaA:
17.09
4v3yB-3efaA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		3 / 3 ALA A  46
TYR A  45
PRO A  63
 None
 0.69A 4zdyA-3efaA:
undetectable		 4zdyA-3efaA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 ASP A  36
ASP A  39
GLU A  34
ILE A  29
 None
None
GOL  A 205 (-3.2A)
None
 0.98A 5cfsA-3efaA:
undetectable		 5cfsA-3efaA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 8 SER A  30
ARG A  19
VAL A  24
PHE A  35
 None
 1.28A 5uo7A-3efaA:
undetectable
5uo7B-3efaA:
undetectable		 5uo7A-3efaA:
15.67
5uo7B-3efaA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3efa PUTATIVE
ACETYLTRANSFERASE
(Lactobacillus
plantarum) 		4 / 5 ASP A  39
ILE A  29
ASN A  11
TYR A  16
 None
 1.18A 6a93B-3efaA:
undetectable		 6a93B-3efaA:
15.85