SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3efc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 12 VAL A 258
LEU A 226
SER A 228
LEU A 231
THR A 243
 None
 0.83A 1kw0A-3efcA:
undetectable		 1kw0A-3efcA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 11 VAL A 258
LEU A 226
SER A 228
LEU A 231
THR A 243
 None
 0.88A 1mmtA-3efcA:
undetectable		 1mmtA-3efcA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 11 SER A 117
VAL A 119
LEU A 165
LEU A 137
LEU A 167
 None
 1.25A 2a15A-3efcA:
undetectable		 2a15A-3efcA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		4 / 6 ALA A  42
VAL A  88
GLU A  90
PHE A  72
 None
 0.98A 2cizA-3efcA:
undetectable		 2cizA-3efcA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		4 / 7 LEU A 226
LEU A 223
PHE A 197
LEU A 193
 None
 0.93A 2vq5B-3efcA:
undetectable		 2vq5B-3efcA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 12 LEU A 311
GLY A 279
ALA A 278
GLY A 275
LEU A 312
 None
 0.96A 3ogqB-3efcA:
undetectable		 3ogqB-3efcA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		4 / 6 SER A 148
TYR A 147
ALA A 149
LEU A 247
 None
 0.99A 3ravA-3efcA:
undetectable		 3ravA-3efcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 10 LEU A 312
LEU A 311
GLY A 313
TYR A 317
ILE A 284
 None
 1.17A 4xj7C-3efcA:
undetectable
4xj7D-3efcA:
undetectable		 4xj7C-3efcA:
22.36
4xj7D-3efcA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_0
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3efc OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR YAET
(Escherichia
coli) 		5 / 12 GLY A 221
ILE A 328
GLY A 263
THR A 261
THR A 225
 None
 1.20A 6e8qA-3efcA:
undetectable		 6e8qA-3efcA:
13.56