SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3efe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 ALA A 153
LYS A 194
PHE A 170
GLY A 164
ILE A 165
 None
 1.20A 1kglA-3efeA:
undetectable		 1kglA-3efeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 6 TYR A 190
GLY A 164
PHE A 170
SER A 163
 None
 1.28A 2a3cA-3efeA:
undetectable		 2a3cA-3efeA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 6 TYR A 190
GLY A 164
PHE A 170
SER A 163
 None
 1.36A 2a3cB-3efeA:
undetectable		 2a3cB-3efeA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_A_SAMA500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 11 THR A 113
GLU A  18
ALA A 166
ALA A 171
PRO A 152
 None
 1.27A 2admA-3efeA:
undetectable		 2admA-3efeA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 11 THR A 113
GLU A  18
ALA A 166
ALA A 171
PRO A 152
 None
 1.28A 2admB-3efeA:
undetectable		 2admB-3efeA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		3 / 3 LEU A 168
PRO A 167
ARG A  30
 None
 0.59A 4klrB-3efeA:
undetectable		 4klrB-3efeA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		4 / 6 SER A  64
LEU A  65
ASP A  66
TYR A   9
 None
 1.03A 4wozA-3efeA:
undetectable
4wozB-3efeA:
undetectable		 4wozA-3efeA:
24.83
4wozB-3efeA:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		3 / 3 LYS A  40
ILE A  42
ILE A  63
 None
 0.57A 4y0qA-3efeA:
undetectable		 4y0qA-3efeA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		3 / 3 LEU A 183
LEU A 186
TRP A 189
 None
 0.93A 5nwuA-3efeA:
undetectable		 5nwuA-3efeA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 PRO A  61
ILE A  23
VAL A  10
LEU A  22
LEU A  75
 None
 1.22A 6b52A-3efeA:
undetectable		 6b52A-3efeA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 12 GLY A  80
ALA A 112
PHE A 170
GLU A  25
VAL A 174
 None
 1.19A 6bqgA-3efeA:
undetectable		 6bqgA-3efeA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3efe THIJ/PFPI FAMILY
PROTEIN
(Bacillus
anthracis) 		5 / 10 GLU A  18
GLY A  80
GLY A  81
ILE A 109
GLY A 164
 None
 0.49A 6e5zA-3efeA:
19.8		 6e5zA-3efeA:
25.91