SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RAV_A_RAVA183_1 (FERRITIN LIGHT CHAIN)	3eff	VOLTAGE-GATED POTASSIUM CHANNEL (Streptomyces lividans)	4 / 6	LEU K 41 SER K 44 TYR K 45 ALA K 65	None	0.91A	3ravA-3effK: 2.1	3ravA-3effK: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RD0_A_EDPA175_1 (FERRITIN LIGHT CHAIN)	3eff	VOLTAGE-GATED POTASSIUM CHANNEL (Streptomyces lividans)	4 / 6	LEU K 41 SER K 44 TYR K 45 ALA K 65	None	0.91A	3rd0A-3effK: 2.2	3rd0A-3effK: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4D7H_A_H4BA902_1 (NITRIC OXIDE SYNTHASE OXYGENASE)	3eff	VOLTAGE-GATED POTASSIUM CHANNEL (Streptomyces lividans)	3 / 3	ARG K 117 THR K 112 TRP K 113	None	1.14A	4d7hA-3effK: 3.6	4d7hA-3effK: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0U_F_ASWF101_1 (DNA TOPOISOMERASE 2-BETA)	3eff	VOLTAGE-GATED POTASSIUM CHANNEL (Streptomyces lividans)	4 / 6	ARG K 89 GLY K 88 ALA K 57 GLU K 51	None	1.07A	4g0uA-3effK: undetectable	4g0uA-3effK: 9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UGL_A_H4BA902_1 (NITRIC OXIDE SYNTHASE)	3eff	VOLTAGE-GATED POTASSIUM CHANNEL (Streptomyces lividans)	3 / 3	ARG K 117 THR K 112 TRP K 113	None	1.17A	4uglA-3effK: 3.3	4uglA-3effK: 17.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3RAV_A_RAVA183_1","FERRITIN LIGHT CHAIN","3eff","VOLTAGE-GATED POTASSIUM CHANNEL","Streptomyces lividans",4,"LEU K  41;SER K  44;TYR K  45;ALA K  65","None","0.91A","3ravA-3effK:2.1","3ravA-3effK:25.00"],["3RD0_A_EDPA175_1","FERRITIN LIGHT CHAIN","3eff","VOLTAGE-GATED POTASSIUM CHANNEL","Streptomyces lividans",4,"LEU K  41;SER K  44;TYR K  45;ALA K  65","None","0.91A","3rd0A-3effK:2.2","3rd0A-3effK:25.00"],["4D7H_A_H4BA902_1","NITRIC OXIDE SYNTHASE OXYGENASE","3eff","VOLTAGE-GATED POTASSIUM CHANNEL","Streptomyces lividans",3,"ARG K 117;THR K 112;TRP K 113","None","1.14A","4d7hA-3effK:3.6","4d7hA-3effK:17.36"],["4G0U_F_ASWF101_1","DNA TOPOISOMERASE 2-BETA","3eff","VOLTAGE-GATED POTASSIUM CHANNEL","Streptomyces lividans",4,"ARG K  89;GLY K  88;ALA K  57;GLU K  51","None","1.07A","4g0uA-3effK:undetectable","4g0uA-3effK:9.25"],["4UGL_A_H4BA902_1","NITRIC OXIDE SYNTHASE","3eff","VOLTAGE-GATED POTASSIUM CHANNEL","Streptomyces lividans",3,"ARG K 117;THR K 112;TRP K 113","None","1.17A","4uglA-3effK:3.3","4uglA-3effK:17.36"]]