SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3efv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 THR A  76
GLY A 308
LEU A 301
ASP A 299
 None
 0.72A 1aegA-3efvA:
undetectable		 1aegA-3efvA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifA-3efvA:
3.4		 1kifA-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifB-3efvA:
3.4		 1kifB-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifC-3efvA:
3.4		 1kifC-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifD-3efvA:
3.4		 1kifD-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifE-3efvA:
3.5		 1kifE-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifF-3efvA:
3.4		 1kifF-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifG-3efvA:
3.5		 1kifG-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.28A 1kifH-3efvA:
3.4		 1kifH-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 ASN A 137
ALA A 311
ASN A 164
 NAD  A 463 (-3.3A)
None
None
 0.74A 1n4fA-3efvA:
undetectable		 1n4fA-3efvA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 TRP A 141
LEU A  64
THR A  91
CYH A  97
 None
 1.39A 1uw6P-3efvA:
undetectable
1uw6T-3efvA:
undetectable		 1uw6P-3efvA:
17.49
1uw6T-3efvA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.27A 1ve9A-3efvA:
3.4		 1ve9A-3efvA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 10 ARG A 411
LEU A 404
LEU A 244
ILE A 242
ALA A 380
 None
 0.93A 2bxeB-3efvA:
undetectable		 2bxeB-3efvA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 11 LEU A 393
VAL A 429
ALA A 430
LEU A 443
SER A 425
 NAD  A 463 ( 4.6A)
None
None
None
None
 1.29A 2c12F-3efvA:
1.7		 2c12F-3efvA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.32A 2du8G-3efvA:
3.6		 2du8G-3efvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 TYR A 157
TYR A 186
ILE A 172
GLY A 146
 None
 1.36A 2du8J-3efvA:
3.4		 2du8J-3efvA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 6 SER A 389
SER A 437
LEU A 393
GLY A 392
 None
None
NAD  A 463 ( 4.6A)
None
 0.91A 2j2pA-3efvA:
undetectable
2j2pC-3efvA:
undetectable		 2j2pA-3efvA:
17.95
2j2pC-3efvA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 6 SER A 389
SER A 437
LEU A 393
GLY A 392
 None
None
NAD  A 463 ( 4.6A)
None
 0.90A 2j2pD-3efvA:
undetectable
2j2pF-3efvA:
undetectable		 2j2pD-3efvA:
17.95
2j2pF-3efvA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 7 GLU A 318
LEU A 315
MET A 297
TYR A 261
 None
 1.18A 2w8yA-3efvA:
undetectable		 2w8yA-3efvA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 MET A 107
CYH A 452
PRO A 149
 None
 1.24A 3h52C-3efvA:
undetectable		 3h52C-3efvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A 187
VAL A 185
LEU A 131
MET A 199
LEU A  35
 None
 1.13A 3h52D-3efvA:
undetectable		 3h52D-3efvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 10 VAL A 196
ILE A 200
ALA A 218
VAL A 210
VAL A 208
 NAD  A 463 (-4.2A)
None
None
None
None
 1.09A 3me6A-3efvA:
undetectable		 3me6A-3efvA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 9 VAL A 196
ILE A 200
ALA A 218
VAL A 210
VAL A 208
 NAD  A 463 (-4.2A)
None
None
None
None
 1.15A 3me6C-3efvA:
undetectable		 3me6C-3efvA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 GLY A 237
ASP A 239
GLN A 266
MET A  79
 None
 1.38A 3qx3B-3efvA:
undetectable		 3qx3B-3efvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 11 PRO A 300
PRO A 309
THR A  16
GLY A  17
ASP A 299
 None
 1.36A 3t8nD-3efvA:
undetectable
3t8nF-3efvA:
undetectable		 3t8nD-3efvA:
16.04
3t8nF-3efvA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 ALA A 147
ASP A  59
ILE A  60
ILE A 175
 None
 0.90A 4kttB-3efvA:
undetectable		 4kttB-3efvA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 GLY A 308
PRO A 309
GLN A 266
 None
 0.26A 4oltB-3efvA:
undetectable		 4oltB-3efvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A 195
GLN A 198
ALA A 191
VAL A 189
LEU A 131
 None
 0.91A 4pd5A-3efvA:
undetectable		 4pd5A-3efvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A 195
GLN A 198
ALA A 191
VAL A 189
LEU A 158
 None
 1.02A 4pd5A-3efvA:
undetectable		 4pd5A-3efvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A 195
GLN A 198
ALA A 191
VAL A 189
LEU A 131
 None
 0.97A 4pd9A-3efvA:
undetectable		 4pd9A-3efvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 GLY A 195
GLN A 198
ALA A 191
VAL A 189
LEU A 158
 None
 1.03A 4pd9A-3efvA:
undetectable		 4pd9A-3efvA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 GLY A 308
PRO A 309
GLN A 266
 None
 0.21A 4qwpB-3efvA:
undetectable		 4qwpB-3efvA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 PHE A 138
VAL A 143
THR A 211
ARG A 145
GLY A 433
 None
None
NAD  A 463 (-4.0A)
NAD  A 463 (-2.7A)
None
 1.26A 4ydqB-3efvA:
3.4		 4ydqB-3efvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		3 / 3 VAL A 355
ARG A 316
PRO A 369
 None
 0.84A 5koxA-3efvA:
undetectable		 5koxA-3efvA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		5 / 12 LEU A 307
ASP A 306
PHE A 138
ALA A 270
GLY A 259
 None
 1.05A 5uxdB-3efvA:
undetectable		 5uxdB-3efvA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 5 GLY A 237
ASP A 239
GLN A 266
MET A  79
 None
 1.36A 5zrfB-3efvA:
undetectable		 5zrfB-3efvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(Salmonella
enterica) 		4 / 8 THR A 209
VAL A 232
LYS A 230
GLU A 234
 None
None
None
NAD  A 463 (-4.1A)
 0.88A 6fbvC-3efvA:
undetectable		 6fbvC-3efvA:
18.01