SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ega'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3ega PROTEIN PELLINO
HOMOLOG 2
(Homo
sapiens) 		5 / 12 ILE A 246
SER A 244
ILE A 155
CYH A 141
VAL A 104
 None
 1.14A 2ft9A-3egaA:
undetectable		 2ft9A-3egaA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ega PROTEIN PELLINO
HOMOLOG 2
(Homo
sapiens) 		3 / 3 LYS A  15
TYR A  46
PRO A  16
 None
 1.28A 2j9cC-3egaA:
undetectable		 2j9cC-3egaA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3ega PROTEIN PELLINO
HOMOLOG 2
(Homo
sapiens) 		3 / 3 TYR A 218
LEU A 245
ARG A 209
 None
 0.80A 3sufB-3egaA:
undetectable		 3sufB-3egaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3ega PROTEIN PELLINO
HOMOLOG 2
(Homo
sapiens) 		5 / 9 LEU A 248
VAL A 190
GLY A 189
THR A 186
VAL A 213
 None
 1.38A 5cp4A-3egaA:
undetectable		 5cp4A-3egaA:
21.07