SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ege'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 43 THR A 44 SER A 64 MET A 67 HIS A 105	EDO A 261 ( 3.9A) None None EDO A 261 ( 4.1A) EDO A 261 ( 4.6A)	0.83A	1nbiC-3egeA: 14.2	1nbiC-3egeA: 24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_D_SAMD3293_0 (GLYCINE N-METHYLTRANSFERASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 43 THR A 44 SER A 64 MET A 67 HIS A 105	EDO A 261 ( 3.9A) None None EDO A 261 ( 4.1A) EDO A 261 ( 4.6A)	0.82A	1nbiD-3egeA: 13.6	1nbiD-3egeA: 24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P91_A_SAMA1401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 11	GLY A 43 GLY A 45 TYR A 47 ILE A 100 LEU A 179	EDO A 261 ( 3.9A) None None None None	1.20A	1p91A-3egeA: 12.8	1p91A-3egeA: 23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_B_SAMB302_0 (HEMK PROTEIN)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	ILE A 40 GLY A 41 GLY A 43 ILE A 100 SER A 64	None EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None	0.87A	1sg9B-3egeA: 4.1	1sg9B-3egeA: 21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_A_SAMA302_0 (HYPOTHETICAL PROTEIN PH0226)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 43 SER A 64 ALA A 84 ILE A 100 HIS A 105	EDO A 261 ( 3.9A) None None None EDO A 261 ( 4.6A)	0.80A	1ve3A-3egeA: 16.1	1ve3A-3egeA: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VE3_B_SAMB301_0 (HYPOTHETICAL PROTEIN PH0226)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 43 SER A 64 ALA A 84 ILE A 100 HIS A 105	EDO A 261 ( 3.9A) None None None EDO A 261 ( 4.6A)	0.85A	1ve3B-3egeA: 16.1	1ve3B-3egeA: 27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	6 / 12	ILE A 40 GLY A 41 GLY A 43 GLU A 85 ILE A 100 HIS A 105	None EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None EDO A 261 ( 4.6A)	1.02A	2fk8A-3egeA: 15.2	2fk8A-3egeA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	6 / 12	ILE A 40 GLY A 41 GLY A 43 ILE A 100 ALA A 102 HIS A 105	None EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None EDO A 261 ( 3.8A) EDO A 261 ( 4.6A)	1.01A	2fk8A-3egeA: 15.2	2fk8A-3egeA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_A_SAMA301_0 (YCGJ)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 ALA A 84 GLU A 85 HIS A 105	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None EDO A 261 ( 4.6A)	0.92A	2gluA-3egeA: 17.3	2gluA-3egeA: 25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 ALA A 84 ALA A 102 HIS A 104 PHE A 106	EDO A 261 (-3.2A) None EDO A 261 ( 3.8A) None None	0.97A	2gluB-3egeA: 16.7	2gluB-3egeA: 25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GLU_B_SAMB302_0 (YCGJ)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	6 / 12	GLY A 41 GLY A 43 ALA A 84 ALA A 102 HIS A 105 PHE A 106	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None EDO A 261 ( 3.8A) EDO A 261 ( 4.6A) None	0.47A	2gluB-3egeA: 16.7	2gluB-3egeA: 25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD2_A_CHDA426_0 (FERROCHELATASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	4 / 4	LEU A 179 PRO A 180 LEU A 183 ARG A 15	None	1.44A	2qd2A-3egeA: 2.2	2qd2A-3egeA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS8_A_BRLA503_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 206 LEU A 101 LEU A 140 LEU A 147 TYR A 141	None	1.33A	3cs8A-3egeA: undetectable	3cs8A-3egeA: 24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_A_CHDA3_0 (FERROCHELATASE, MITOCHONDRIAL)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	4 / 4	LEU A 179 PRO A 180 LEU A 183 ARG A 15	None	1.41A	3hcoA-3egeA: undetectable	3hcoA-3egeA: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MTE_B_SAMB220_0 (16S RRNA METHYLASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 PRO A 63 ALA A 84 GLU A 85	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) EDO A 261 ( 4.9A) None None	0.75A	3mteB-3egeA: 10.3	3mteB-3egeA: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDI_A_SAMA601_1 (METHYLTRANSFERASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 9	GLY A 41 GLU A 62 PRO A 63 SER A 64 HIS A 105	EDO A 261 (-3.2A) EDO A 261 (-3.0A) EDO A 261 ( 4.9A) None EDO A 261 ( 4.6A)	0.94A	3ndiA-3egeA: 11.6	3ndiA-3egeA: 23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXZ_A_0LIA1_2 (TYROSINE-PROTEIN KINASE ABL1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 9	LEU A 179 TYR A 251 VAL A 172 ILE A 175 LEU A 101	None	1.41A	3oxzA-3egeA: undetectable	3oxzA-3egeA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_B_SAMB6735_0 (16S RRNA METHYLASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 PRO A 63 ALA A 84 GLU A 85	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) EDO A 261 ( 4.9A) None None	0.71A	3p2kB-3egeA: 10.6	3p2kB-3egeA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P6H_A_IBPA133_1 (FATTY ACID-BINDING PROTEIN, ADIPOCYTE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	4 / 7	ASP A 182 ILE A 19 VAL A 22 TYR A 47	None	1.06A	3p6hA-3egeA: undetectable	3p6hA-3egeA: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG306_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	3 / 3	ARG A 194 ARG A 20 ASP A 185	None	0.82A	3wipG-3egeA: undetectable 3wipH-3egeA: undetectable	3wipG-3egeA: 23.19 3wipH-3egeA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 SER A 64 ALA A 84 HIS A 105	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None EDO A 261 ( 4.6A)	0.91A	4krhA-3egeA: 16.2	4krhA-3egeA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 SER A 64 ALA A 84 HIS A 105	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None EDO A 261 ( 4.6A)	0.82A	4krhB-3egeA: 10.8	4krhB-3egeA: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MME_A_29QA603_1 (TRANSPORTER)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 9	VAL A 58 ALA A 38 TYR A 59 GLY A 34 GLY A 96	None	1.40A	4mmeA-3egeA: undetectable	4mmeA-3egeA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMF_A_29QA603_1 (TRANSPORTER)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 9	VAL A 58 ALA A 38 TYR A 59 GLY A 34 GLY A 96	None	1.32A	4mmfA-3egeA: undetectable	4mmfA-3egeA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMF_B_29QB603_1 (TRANSPORTER)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 9	VAL A 58 ALA A 38 TYR A 59 GLY A 34 GLY A 96	None	1.32A	4mmfB-3egeA: undetectable	4mmfB-3egeA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_B_SAMB301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	6 / 12	GLY A 41 GLY A 43 SER A 64 MET A 67 ILE A 100 ALA A 102	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None EDO A 261 ( 4.1A) None EDO A 261 ( 3.8A)	0.83A	4qtuB-3egeA: 15.8	4qtuB-3egeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 SER A 64 ILE A 100 ALA A 102	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None None EDO A 261 ( 3.8A)	0.58A	4qtuD-3egeA: 16.4	4qtuD-3egeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 41 GLY A 43 SER A 64 MET A 67 ILE A 100	EDO A 261 (-3.2A) EDO A 261 ( 3.9A) None EDO A 261 ( 4.1A) None	0.79A	4qtuD-3egeA: 16.4	4qtuD-3egeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_A_SAMA301_0 (CAFFEOYL-COA O-METHYLTRANSFERASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 250 ILE A 247 ALA A 189 ALA A 135 TYR A 141	None	1.17A	5kvaA-3egeA: 11.9	5kvaA-3egeA: 22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KVA_B_SAMB301_0 (CAFFEOYL-COA O-METHYLTRANSFERASE)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	GLY A 250 ILE A 247 ALA A 189 ALA A 135 TYR A 141	None	1.13A	5kvaB-3egeA: 11.9	5kvaB-3egeA: 22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_F_Z80F401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 10	ILE A 98 ILE A 37 VAL A 126 THR A 124 ASN A 30	None	1.20A	5lg3F-3egeA: undetectable	5lg3F-3egeA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 10	ILE A 98 ILE A 37 VAL A 126 THR A 124 ASN A 30	None	1.21A	5lg3G-3egeA: undetectable	5lg3G-3egeA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_H_Z80H401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 10	ILE A 98 ILE A 37 VAL A 126 THR A 124 ASN A 30	None	1.20A	5lg3H-3egeA: undetectable	5lg3H-3egeA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_J_Z80J401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 12	ILE A 98 ILE A 37 VAL A 126 THR A 124 ASN A 30	None	1.20A	5lg3J-3egeA: undetectable	5lg3J-3egeA: 23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWU_A_ACAA18_2 (WTFP-TAG,GP41)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	3 / 3	LEU A 222 LEU A 225 TRP A 234	None	0.93A	5nwuA-3egeA: undetectable	5nwuA-3egeA: 10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GP2_A_DAHA126_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE BETA CHAIN)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 11	LEU A 101 SER A 208 GLY A 206 ILE A 207 PHE A 130	None	1.04A	6gp2A-3egeA: undetectable	6gp2A-3egeA: 16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GP2_B_DAHB126_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE BETA CHAIN)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	5 / 11	LEU A 101 SER A 208 GLY A 206 ILE A 207 PHE A 130	None	1.02A	6gp2B-3egeA: undetectable	6gp2B-3egeA: 16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_B_STIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	4 / 7	VAL A 22 ILE A 37 GLY A 82 ALA A 42	None	0.88A	6hd6B-3egeA: undetectable	6hd6B-3egeA: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_C_CHDC305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	3ege	PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY (Trichormus variabilis)	4 / 4	ARG A 118 GLN A 114 PHE A 113 LEU A 87	None	1.35A	6nmfC-3egeA: 0.0	6nmfC-3egeA: 19.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NBI_C_SAMC2293_0","GLYCINE N-METHYLTRANSFERASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  43;THR A  44;SER A  64;MET A  67;HIS A 105","EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.1A);EDO A 261 ( 4.6A)","0.83A","1nbiC-3egeA:14.2","1nbiC-3egeA:24.43"],["1NBI_D_SAMD3293_0","GLYCINE N-METHYLTRANSFERASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  43;THR A  44;SER A  64;MET A  67;HIS A 105","EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.1A);EDO A 261 ( 4.6A)","0.82A","1nbiD-3egeA:13.6","1nbiD-3egeA:24.43"],["1P91_A_SAMA1401_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  43;GLY A  45;TYR A  47;ILE A 100;LEU A 179","EDO A 261 ( 3.9A);None;None;None;None","1.20A","1p91A-3egeA:12.8","1p91A-3egeA:23.84"],["1SG9_B_SAMB302_0","HEMK PROTEIN","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"ILE A  40;GLY A  41;GLY A  43;ILE A 100;SER A  64","None;EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None","0.87A","1sg9B-3egeA:4.1","1sg9B-3egeA:21.36"],["1VE3_A_SAMA302_0","HYPOTHETICAL PROTEIN PH0226","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  43;SER A  64;ALA A  84;ILE A 100;HIS A 105","EDO A 261 ( 3.9A);None;None;None;EDO A 261 ( 4.6A)","0.80A","1ve3A-3egeA:16.1","1ve3A-3egeA:27.01"],["1VE3_B_SAMB301_0","HYPOTHETICAL PROTEIN PH0226","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  43;SER A  64;ALA A  84;ILE A 100;HIS A 105","EDO A 261 ( 3.9A);None;None;None;EDO A 261 ( 4.6A)","0.85A","1ve3B-3egeA:16.1","1ve3B-3egeA:27.01"],["2FK8_A_SAMA302_0","METHOXY MYCOLIC ACID SYNTHASE 4","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",6,"ILE A  40;GLY A  41;GLY A  43;GLU A  85;ILE A 100;HIS A 105","None;EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.6A)","1.02A","2fk8A-3egeA:15.2","2fk8A-3egeA:22.71"],["2FK8_A_SAMA302_0","METHOXY MYCOLIC ACID SYNTHASE 4","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",6,"ILE A  40;GLY A  41;GLY A  43;ILE A 100;ALA A 102;HIS A 105","None;EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;EDO A 261 ( 3.8A);EDO A 261 ( 4.6A)","1.01A","2fk8A-3egeA:15.2","2fk8A-3egeA:22.71"],["2GLU_A_SAMA301_0","YCGJ","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;ALA A  84;GLU A  85;HIS A 105","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.6A)","0.92A","2gluA-3egeA:17.3","2gluA-3egeA:25.93"],["2GLU_B_SAMB302_0","YCGJ","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;ALA A  84;ALA A 102;HIS A 104;PHE A 106","EDO A 261 (-3.2A);None;EDO A 261 ( 3.8A);None;None","0.97A","2gluB-3egeA:16.7","2gluB-3egeA:25.93"],["2GLU_B_SAMB302_0","YCGJ","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",6,"GLY A  41;GLY A  43;ALA A  84;ALA A 102;HIS A 105;PHE A 106","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;EDO A 261 ( 3.8A);EDO A 261 ( 4.6A);None","0.47A","2gluB-3egeA:16.7","2gluB-3egeA:25.93"],["2QD2_A_CHDA426_0","FERROCHELATASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",4,"LEU A 179;PRO A 180;LEU A 183;ARG A  15","None","1.44A","2qd2A-3egeA:2.2","2qd2A-3egeA:21.01"],["3CS8_A_BRLA503_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A 206;LEU A 101;LEU A 140;LEU A 147;TYR A 141","None","1.33A","3cs8A-3egeA:undetectable","3cs8A-3egeA:24.53"],["3HCO_A_CHDA3_0","FERROCHELATASE, MITOCHONDRIAL","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",4,"LEU A 179;PRO A 180;LEU A 183;ARG A  15","None","1.41A","3hcoA-3egeA:undetectable","3hcoA-3egeA:21.01"],["3MTE_B_SAMB220_0","16S RRNA METHYLASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;PRO A  63;ALA A  84;GLU A  85","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);EDO A 261 ( 4.9A);None;None","0.75A","3mteB-3egeA:10.3","3mteB-3egeA:21.98"],["3NDI_A_SAMA601_1","METHYLTRANSFERASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLU A  62;PRO A  63;SER A  64;HIS A 105","EDO A 261 (-3.2A);EDO A 261 (-3.0A);EDO A 261 ( 4.9A);None;EDO A 261 ( 4.6A)","0.94A","3ndiA-3egeA:11.6","3ndiA-3egeA:23.02"],["3OXZ_A_0LIA1_2","TYROSINE-PROTEIN KINASE ABL1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"LEU A 179;TYR A 251;VAL A 172;ILE A 175;LEU A 101","None","1.41A","3oxzA-3egeA:undetectable","3oxzA-3egeA:21.12"],["3P2K_B_SAMB6735_0","16S RRNA METHYLASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;PRO A  63;ALA A  84;GLU A  85","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);EDO A 261 ( 4.9A);None;None","0.71A","3p2kB-3egeA:10.6","3p2kB-3egeA:21.90"],["3P6H_A_IBPA133_1","FATTY ACID-BINDING PROTEIN, ADIPOCYTE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",4,"ASP A 182;ILE A  19;VAL A  22;TYR A  47","None","1.06A","3p6hA-3egeA:undetectable","3p6hA-3egeA:18.70"],["3WIP_G_ACTG306_0","ACETYLCHOLINE-BINDING PROTEIN","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",3,"ARG A 194;ARG A  20;ASP A 185","None","0.82A","3wipG-3egeA:undetectable;3wipH-3egeA:undetectable","3wipG-3egeA:23.19;3wipH-3egeA:23.19"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;SER A  64;ALA A  84;HIS A 105","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.6A)","0.91A","4krhA-3egeA:16.2","4krhA-3egeA:20.20"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;SER A  64;ALA A  84;HIS A 105","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None;EDO A 261 ( 4.6A)","0.82A","4krhB-3egeA:10.8","4krhB-3egeA:20.20"],["4MME_A_29QA603_1","TRANSPORTER","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"VAL A  58;ALA A  38;TYR A  59;GLY A  34;GLY A  96","None","1.40A","4mmeA-3egeA:undetectable","4mmeA-3egeA:19.14"],["4MMF_A_29QA603_1","TRANSPORTER","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"VAL A  58;ALA A  38;TYR A  59;GLY A  34;GLY A  96","None","1.32A","4mmfA-3egeA:undetectable","4mmfA-3egeA:19.14"],["4MMF_B_29QB603_1","TRANSPORTER","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"VAL A  58;ALA A  38;TYR A  59;GLY A  34;GLY A  96","None","1.32A","4mmfB-3egeA:undetectable","4mmfB-3egeA:19.14"],["4QTU_B_SAMB301_0","PUTATIVE METHYLTRANSFERASE BUD23","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",6,"GLY A  41;GLY A  43;SER A  64;MET A  67;ILE A 100;ALA A 102","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;EDO A 261 ( 4.1A);None;EDO A 261 ( 3.8A)","0.83A","4qtuB-3egeA:15.8","4qtuB-3egeA:22.22"],["4QTU_D_SAMD301_0","PUTATIVE METHYLTRANSFERASE BUD23","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;SER A  64;ILE A 100;ALA A 102","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;None;EDO A 261 ( 3.8A)","0.58A","4qtuD-3egeA:16.4","4qtuD-3egeA:22.22"],["4QTU_D_SAMD301_0","PUTATIVE METHYLTRANSFERASE BUD23","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A  41;GLY A  43;SER A  64;MET A  67;ILE A 100","EDO A 261 (-3.2A);EDO A 261 ( 3.9A);None;EDO A 261 ( 4.1A);None","0.79A","4qtuD-3egeA:16.4","4qtuD-3egeA:22.22"],["5KVA_A_SAMA301_0","CAFFEOYL-COA O-METHYLTRANSFERASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A 250;ILE A 247;ALA A 189;ALA A 135;TYR A 141","None","1.17A","5kvaA-3egeA:11.9","5kvaA-3egeA:22.29"],["5KVA_B_SAMB301_0","CAFFEOYL-COA O-METHYLTRANSFERASE","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"GLY A 250;ILE A 247;ALA A 189;ALA A 135;TYR A 141","None","1.13A","5kvaB-3egeA:11.9","5kvaB-3egeA:22.29"],["5LG3_F_Z80F401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"ILE A  98;ILE A  37;VAL A 126;THR A 124;ASN A  30","None","1.20A","5lg3F-3egeA:undetectable","5lg3F-3egeA:23.17"],["5LG3_G_Z80G401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"ILE A  98;ILE A  37;VAL A 126;THR A 124;ASN A  30","None","1.21A","5lg3G-3egeA:undetectable","5lg3G-3egeA:23.17"],["5LG3_H_Z80H401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"ILE A  98;ILE A  37;VAL A 126;THR A 124;ASN A  30","None","1.20A","5lg3H-3egeA:undetectable","5lg3H-3egeA:23.17"],["5LG3_J_Z80J401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"ILE A  98;ILE A  37;VAL A 126;THR A 124;ASN A  30","None","1.20A","5lg3J-3egeA:undetectable","5lg3J-3egeA:23.17"],["5NWU_A_ACAA18_2","WTFP-TAG,GP41","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",3,"LEU A 222;LEU A 225;TRP A 234","None","0.93A","5nwuA-3egeA:undetectable","5nwuA-3egeA:10.34"],["6GP2_A_DAHA126_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"LEU A 101;SER A 208;GLY A 206;ILE A 207;PHE A 130","None","1.04A","6gp2A-3egeA:undetectable","6gp2A-3egeA:16.94"],["6GP2_B_DAHB126_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",5,"LEU A 101;SER A 208;GLY A 206;ILE A 207;PHE A 130","None","1.02A","6gp2B-3egeA:undetectable","6gp2B-3egeA:16.94"],["6HD6_B_STIB601_1","TYROSINE-PROTEIN KINASE ABL1","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",4,"VAL A  22;ILE A  37;GLY A  82;ALA A  42","None","0.88A","6hd6B-3egeA:undetectable","6hd6B-3egeA:15.04"],["6NMF_C_CHDC305_0","CYTOCHROME C OXIDASE SUBUNIT 3","3ege","PUTATIVE METHYLTRANSFERASE FROM ANTIBIOTIC BIOSYNTHESIS PATHWAY","Trichormus variabilis",4,"ARG A 118;GLN A 114;PHE A 113;LEU A  87","None","1.35A","6nmfC-3egeA:0.0","6nmfC-3egeA:19.93"]]