SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3egj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 8 LEU A 267
ALA A 328
LEU A   4
LEU A  51
SER A  52
 None
 1.31A 1dvtA-3egjA:
undetectable
1dvtB-3egjA:
undetectable		 1dvtA-3egjA:
16.01
1dvtB-3egjA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 HIS A 140
HIS A 192
HIS A 213
ASP A 270
 NI  A 401 (-4.4A)
NI  A 401 (-3.4A)
NI  A 401 (-3.7A)
NI  A 401 ( 4.8A)
 0.94A 1e9yB-3egjA:
19.5		 1e9yB-3egjA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 GLY A 191
ALA A 200
THR A 219
THR A 193
ALA A 231
 None
 1.47A 1gtnO-3egjA:
undetectable
1gtnP-3egjA:
undetectable		 1gtnO-3egjA:
12.82
1gtnP-3egjA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 9 GLY A 191
ALA A 200
THR A 219
THR A 193
ALA A 231
 None
 1.46A 1gtnQ-3egjA:
undetectable
1gtnR-3egjA:
undetectable		 1gtnQ-3egjA:
12.82
1gtnR-3egjA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLU A 128
HIS A 140
HIS A 192
HIS A 213
ASP A 270
 NI  A 401 (-2.7A)
NI  A 401 (-4.4A)
NI  A 401 (-3.4A)
NI  A 401 (-3.7A)
NI  A 401 ( 4.8A)
 1.23A 1ituA-3egjA:
15.4		 1ituA-3egjA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLU A 128
HIS A 140
HIS A 192
HIS A 213
ASP A 270
 NI  A 401 (-2.7A)
NI  A 401 (-4.4A)
NI  A 401 (-3.4A)
NI  A 401 (-3.7A)
NI  A 401 ( 4.8A)
 1.26A 1ituB-3egjA:
15.5		 1ituB-3egjA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 GLU A 128
HIS A 192
HIS A 140
 NI  A 401 (-2.7A)
NI  A 401 (-3.4A)
NI  A 401 (-4.4A)
 0.68A 1oe2A-3egjA:
undetectable		 1oe2A-3egjA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 GLY A  54
ILE A  56
VAL A 371
SER A  91
 None
 1.13A 1rs7A-3egjA:
undetectable		 1rs7A-3egjA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.99A 1sduB-3egjA:
undetectable		 1sduB-3egjA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 7 LEU A  60
PHE A  92
TYR A 114
THR A  73
 None
 1.11A 2eikA-3egjA:
undetectable
2eikJ-3egjA:
undetectable		 2eikA-3egjA:
22.35
2eikJ-3egjA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 1.02A 2hs2B-3egjA:
undetectable		 2hs2B-3egjA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 ALA A 271
GLY A  64
SER A  87
 None
 0.59A 2ivuA-3egjA:
undetectable		 2ivuA-3egjA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 1.00A 2o4lA-3egjA:
undetectable		 2o4lA-3egjA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.96A 2pymB-3egjA:
undetectable		 2pymB-3egjA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 ASP A 363
ASN A 365
THR A 358
 None
 0.75A 2pymB-3egjA:
undetectable		 2pymB-3egjA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.98A 2pynB-3egjA:
undetectable		 2pynB-3egjA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.97A 2q63B-3egjA:
undetectable		 2q63B-3egjA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 7 LEU A  60
PHE A  92
TYR A 114
THR A  73
 None
 1.10A 2zxwN-3egjA:
undetectable
2zxwW-3egjA:
undetectable		 2zxwN-3egjA:
22.35
2zxwW-3egjA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.97A 3d1xB-3egjA:
undetectable		 3d1xB-3egjA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 11 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.91A 3em4U-3egjA:
undetectable		 3em4U-3egjA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 MET A   1
CYH A  32
PRO A  38
 None
 1.23A 3h52C-3egjA:
undetectable		 3h52C-3egjA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 HIS A 192
THR A 167
THR A 212
LEU A 132
GLY A 129
 NI  A 401 (-3.4A)
None
None
None
None
 1.40A 3h9uB-3egjA:
undetectable		 3h9uB-3egjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 HIS A 192
THR A 167
THR A 212
LEU A 132
GLY A 129
 NI  A 401 (-3.4A)
None
None
None
None
 1.42A 3h9uC-3egjA:
undetectable		 3h9uC-3egjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 HIS A 192
THR A 167
THR A 212
LEU A 132
GLY A 129
 NI  A 401 (-3.4A)
None
None
None
None
 1.40A 3h9uD-3egjA:
undetectable		 3h9uD-3egjA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_C_MTXC613_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 ALA A 271
PHE A  92
SER A  91
THR A  76
THR A 269
 None
 1.00A 3hj3C-3egjA:
undetectable		 3hj3C-3egjA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 4 ASP A  26
GLY A  25
LYS A  27
GLU A  29
 None
 1.35A 3hznD-3egjA:
undetectable		 3hznD-3egjA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 SER A 306
ASP A 245
ASN A 316
 None
 0.86A 3lsfB-3egjA:
undetectable
3lsfE-3egjA:
undetectable		 3lsfB-3egjA:
23.51
3lsfE-3egjA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 ASP A 245
ASN A 316
SER A 306
 None
 0.83A 3lsfB-3egjA:
undetectable
3lsfE-3egjA:
undetectable		 3lsfB-3egjA:
23.51
3lsfE-3egjA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.93A 3nduA-3egjA:
undetectable		 3nduA-3egjA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.95A 3nduB-3egjA:
undetectable		 3nduB-3egjA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.97A 3ndxA-3egjA:
undetectable		 3ndxA-3egjA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 11 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.88A 3ndxB-3egjA:
undetectable		 3ndxB-3egjA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 0.97A 3pwmB-3egjA:
undetectable		 3pwmB-3egjA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 GLY A 241
ALA A 240
ILE A 260
VAL A 228
ILE A 232
 None
 0.96A 3pwrB-3egjA:
undetectable		 3pwrB-3egjA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 CYH A  63
PRO A  94
THR A  76
THR A 309
 None
 1.26A 3q07A-3egjA:
undetectable		 3q07A-3egjA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 CYH A  63
PRO A  94
THR A  76
THR A 309
 None
 1.25A 3q07B-3egjA:
undetectable		 3q07B-3egjA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 TYR A 375
TYR A   2
ILE A  23
VAL A 370
ILE A 349
 None
 1.41A 3uprA-3egjA:
undetectable		 3uprA-3egjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 TYR A 375
TYR A   2
ILE A  23
VAL A 370
ILE A 349
 None
 1.43A 3uprC-3egjA:
undetectable		 3uprC-3egjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 7 ALA A 324
ILE A 323
ARG A 330
HIS A 258
 None
 0.75A 3v4tH-3egjA:
undetectable		 3v4tH-3egjA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 GLY A  54
ILE A  56
VAL A 371
SER A  91
 None
 1.25A 4d33A-3egjA:
undetectable		 4d33A-3egjA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 0.80A 4dqfB-3egjA:
undetectable		 4dqfB-3egjA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 6 PHE A  55
ALA A 332
ALA A 313
THR A 317
 None
 1.02A 4dtzA-3egjA:
undetectable		 4dtzA-3egjA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 7 ASN A 356
GLY A 347
ILE A 340
LEU A 123
 None
 0.78A 4ejjD-3egjA:
undetectable		 4ejjD-3egjA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 ALA A 231
SER A 206
ILE A 178
PRO A 175
ASN A 173
 None
 1.29A 4gh8B-3egjA:
undetectable		 4gh8B-3egjA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 5 HIS A 140
HIS A 192
HIS A 213
ASP A 270
 NI  A 401 (-4.4A)
NI  A 401 (-3.4A)
NI  A 401 (-3.7A)
NI  A 401 ( 4.8A)
 0.95A 4h9mA-3egjA:
21.3		 4h9mA-3egjA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		4 / 7 SER A  91
LYS A 338
LEU A 334
ALA A 337
 None
 1.03A 4ikkA-3egjA:
undetectable
4ikkB-3egjA:
undetectable		 4ikkA-3egjA:
16.09
4ikkB-3egjA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		3 / 3 VAL A 228
ALA A 211
PHE A 204
 None
 0.79A 4olbA-3egjA:
undetectable		 4olbA-3egjA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 TYR A 375
TYR A   2
ILE A  23
VAL A 370
ILE A 349
 None
 1.45A 5u98A-3egjA:
undetectable		 5u98A-3egjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 10 TYR A 375
TYR A   2
ILE A  23
VAL A 370
ILE A 349
 None
 1.47A 5u98D-3egjA:
undetectable		 5u98D-3egjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 0.95A 6dh6A-3egjA:
undetectable		 6dh6A-3egjA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 LEU A 181
ASP A 161
GLY A 124
VAL A 188
ILE A 186
 None
 1.01A 6difA-3egjA:
undetectable		 6difA-3egjA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IEY_A_CLMA401_0
(ESTERASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 11 ILE A  72
LEU A 127
GLY A 124
SER A 122
PHE A  68
 None
 1.05A 6ieyA-3egjA:
undetectable
6ieyB-3egjA:
undetectable		 6ieyA-3egjA:
22.03
6ieyB-3egjA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 HIS A 213
SER A 189
HIS A 192
HIS A 140
ASP A 270
 NI  A 401 (-3.7A)
None
NI  A 401 (-3.4A)
NI  A 401 (-4.4A)
NI  A 401 ( 4.8A)
 1.23A 6n91A-3egjA:
7.4		 6n91A-3egjA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE
(Vibrio
cholerae) 		5 / 12 HIS A 213
SER A 189
HIS A 192
HIS A 140
ASP A 270
 NI  A 401 (-3.7A)
None
NI  A 401 (-3.4A)
NI  A 401 (-4.4A)
NI  A 401 ( 4.8A)
 1.23A 6n91B-3egjA:
16.0		 6n91B-3egjA:
12.77