SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PHE A  41
THR A  92
ALA A  34
SER A  33
MET A  31
 None
 1.24A 1fm4A-3eh0A:
undetectable		 1fm4A-3eh0A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.94A 2nmyB-3eh0A:
undetectable		 2nmyB-3eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.89A 2pymB-3eh0A:
undetectable		 2pymB-3eh0A:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.90A 2pynB-3eh0A:
undetectable		 2pynB-3eh0A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.97A 2q63B-3eh0A:
undetectable		 2q63B-3eh0A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.94A 2qakB-3eh0A:
undetectable		 2qakB-3eh0A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 11 ALA A 219
HIS A 276
GLY A 257
GLY A 184
ILE A 195
 None
 1.12A 2x1lC-3eh0A:
undetectable		 2x1lC-3eh0A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 7 VAL A 158
ILE A 172
GLY A 175
THR A 176
 None
 0.56A 2xrzB-3eh0A:
undetectable		 2xrzB-3eh0A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.85A 3cyxA-3eh0A:
undetectable		 3cyxA-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.94A 3d1xB-3eh0A:
undetectable		 3d1xB-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ALA A 180
VAL A 241
VAL A 158
ILE A 160
THR A 176
 None
 1.25A 3dl9A-3eh0A:
undetectable		 3dl9A-3eh0A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.89A 3ndtB-3eh0A:
undetectable		 3ndtB-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.95A 3ndtC-3eh0A:
undetectable		 3ndtC-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.97A 3nduD-3eh0A:
undetectable		 3nduD-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.99A 3nu3A-3eh0A:
undetectable		 3nu3A-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 1.00A 3oxxA-3eh0A:
undetectable		 3oxxA-3eh0A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.94A 3oxxC-3eh0A:
undetectable		 3oxxC-3eh0A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.92A 3pwrA-3eh0A:
undetectable		 3pwrA-3eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.91A 3pwrB-3eh0A:
undetectable		 3pwrB-3eh0A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.93A 3tkgA-3eh0A:
undetectable		 3tkgA-3eh0A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.99A 3tkgD-3eh0A:
undetectable		 3tkgD-3eh0A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 130
ILE A 166
SER A 146
ILE A 118
ALA A  97
 None
 1.46A 3vw1B-3eh0A:
undetectable		 3vw1B-3eh0A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 5 HIS A 162
SER A 146
SER A 126
VAL A 128
 None
 1.37A 4a99D-3eh0A:
undetectable		 4a99D-3eh0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		4 / 8 ASP A 232
VAL A 285
SER A 303
GLY A 287
 None
 0.76A 4acaC-3eh0A:
undetectable		 4acaC-3eh0A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.96A 4jecB-3eh0A:
undetectable		 4jecB-3eh0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 160
VAL A 128
 None
 0.87A 4xdrA-3eh0A:
undetectable		 4xdrA-3eh0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 PRO A  96
VAL A 207
ASP A 232
ASN A 233
ILE A 172
 None
 1.36A 4xe0A-3eh0A:
undetectable		 4xe0A-3eh0A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		3 / 3 VAL A 249
GLN A 236
CYH A 235
 None
 0.83A 5icxA-3eh0A:
undetectable
5icxE-3eh0A:
undetectable		 5icxA-3eh0A:
21.13
5icxE-3eh0A:
4.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 10 ILE A 231
ILE A 225
VAL A 249
THR A 247
ILE A 261
 None
 1.14A 5lg3F-3eh0A:
undetectable		 5lg3F-3eh0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 10 ILE A 231
ILE A 225
VAL A 249
THR A 247
ILE A 261
 None
 1.14A 5lg3G-3eh0A:
undetectable		 5lg3G-3eh0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 10 ILE A 231
ILE A 225
VAL A 249
THR A 247
ILE A 261
 None
 1.14A 5lg3H-3eh0A:
undetectable		 5lg3H-3eh0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 ILE A 231
ILE A 225
VAL A 249
THR A 247
ILE A 261
 None
 1.20A 5lg3J-3eh0A:
undetectable		 5lg3J-3eh0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.97A 6dh3B-3eh0A:
undetectable		 6dh3B-3eh0A:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3eh0 UDP-3-O-[3-HYDROXYMY
RISTOYL] GLUCOSAMINE
N-ACYLTRANSFERASE
(Escherichia
coli) 		5 / 12 LEU A 154
GLY A 139
ALA A 122
ILE A 106
ILE A 136
 None
 0.93A 6dh6B-3eh0A:
undetectable		 6dh6B-3eh0A:
11.66