SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ehd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3ehd UNCHARACTERIZED
CONSERVED PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A  56
ALA A  57
ASP A  60
THR A  61
VAL A  89
 None
None
GOL  A1001 (-4.2A)
None
None
 0.99A 3s79A-3ehdA:
undetectable		 3s79A-3ehdA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 3ehd UNCHARACTERIZED
CONSERVED PROTEIN
(Enterococcus
faecalis) 		5 / 10 ILE A  56
ALA A  57
ASP A  60
THR A  61
VAL A  89
 None
None
GOL  A1001 (-4.2A)
None
None
 0.96A 4kq8A-3ehdA:
undetectable		 4kq8A-3ehdA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 3ehd UNCHARACTERIZED
CONSERVED PROTEIN
(Enterococcus
faecalis) 		5 / 12 ILE A  56
ALA A  57
ASP A  60
THR A  61
VAL A  89
 None
None
GOL  A1001 (-4.2A)
None
None
 0.98A 5jkvA-3ehdA:
undetectable		 5jkvA-3ehdA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3ehd UNCHARACTERIZED
CONSERVED PROTEIN
(Enterococcus
faecalis) 		4 / 8 LEU A  22
VAL A  71
LEU A  29
ILE A   4
 None
 0.91A 5v0vA-3ehdA:
undetectable		 5v0vA-3ehdA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3ehd UNCHARACTERIZED
CONSERVED PROTEIN
(Enterococcus
faecalis) 		4 / 9 VAL A  83
ASP A  80
LEU A  37
ASP A  15
 GOL  A1001 ( 4.5A)
GOL  A1001 (-3.0A)
None
None
 1.00A 6c2mD-3ehdA:
undetectable		 6c2mD-3ehdA:
16.25