SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ehe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 7 ILE A 205
ARG A 164
THR A 126
LEU A 271
 None
 0.92A 1v55A-3eheA:
undetectable
1v55J-3eheA:
undetectable		 1v55A-3eheA:
17.73
1v55J-3eheA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 5 ILE A 162
LEU A 143
ALA A 147
GLU A 150
 None
 0.82A 1xvaA-3eheA:
6.6
1xvaB-3eheA:
6.7		 1xvaA-3eheA:
19.58
1xvaB-3eheA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		3 / 3 TRP A 282
LEU A 215
LYS A  20
 None
 1.32A 1yajK-3eheA:
2.1		 1yajK-3eheA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 213
ASP A 212
ASP A 209
ILE A 205
ILE A 229
 None
 0.99A 2hs1A-3eheA:
undetectable		 2hs1A-3eheA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 8 ILE A 205
ARG A 164
THR A 126
LEU A 271
 None
 0.88A 3abkA-3eheA:
undetectable
3abkJ-3eheA:
undetectable		 3abkA-3eheA:
17.73
3abkJ-3eheA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 7 ILE A 205
ARG A 164
THR A 126
LEU A 271
 None
 0.95A 3ag3A-3eheA:
undetectable
3ag3J-3eheA:
undetectable		 3ag3A-3eheA:
17.73
3ag3J-3eheA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		5 / 12 GLY A  11
GLY A  36
ILE A  27
GLY A   8
GLY A   9
 NAD  A 900 (-3.3A)
NAD  A 900 (-3.0A)
None
NAD  A 900 (-3.6A)
None
 1.08A 3axzA-3eheA:
undetectable		 3axzA-3eheA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 6 ILE A 205
ARG A 164
THR A 126
LEU A 271
 None
 0.86A 3wg7N-3eheA:
undetectable
3wg7W-3eheA:
undetectable		 3wg7N-3eheA:
17.73
3wg7W-3eheA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 240
ILE A 178
GLY A 176
SER A 208
GLY A 170
 None
 0.97A 4ac9B-3eheA:
5.5
4ac9C-3eheA:
5.5		 4ac9B-3eheA:
20.78
4ac9C-3eheA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 9 TYR A 206
PHE A  12
HIS A  16
ILE A 178
 None
 1.10A 4jvlA-3eheA:
undetectable		 4jvlA-3eheA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_H_SPMH202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 287
GLU A 289
TYR A 206
GLU A 290
 None
 1.43A 4r87H-3eheA:
undetectable		 4r87H-3eheA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		5 / 8 GLY A 170
SER A 173
PHE A  12
SER A  15
HIS A  16
 None
 1.27A 4ws1A-3eheA:
undetectable		 4ws1A-3eheA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 185
THR A 257
LEU A 195
ILE A 235
PHE A 181
 None
 1.36A 5dlvB-3eheA:
undetectable		 5dlvB-3eheA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ehe UDP-GLUCOSE
4-EPIMERASE (GALE-1)
(Archaeoglobus
fulgidus) 		4 / 6 ILE A 205
ARG A 164
THR A 126
LEU A 271
 None
 0.98A 5z86N-3eheA:
undetectable
5z86W-3eheA:
undetectable		 5z86N-3eheA:
17.73
5z86W-3eheA:
10.60