SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ehf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3ehf SENSOR KINASE (YOCF
PROTEIN)
(Bacillus
subtilis) 		4 / 5 ASP A 321
ARG A 304
VAL A 291
THR A 362
 None
 1.23A 3eigA-3ehfA:
undetectable		 3eigA-3ehfA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ehf SENSOR KINASE (YOCF
PROTEIN)
(Bacillus
subtilis) 		4 / 8 PHE A 264
VAL A 305
MET A 363
ILE A 316
 None
 1.06A 4a97I-3ehfA:
4.5		 4a97I-3ehfA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3ehf SENSOR KINASE (YOCF
PROTEIN)
(Bacillus
subtilis) 		5 / 11 GLY A 358
ASP A 321
ALA A 300
GLY A 322
CYH A 303
 None
 1.33A 4c5lA-3ehfA:
undetectable		 4c5lA-3ehfA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 3ehf SENSOR KINASE (YOCF
PROTEIN)
(Bacillus
subtilis) 		5 / 12 LEU A 287
LEU A 344
VAL A 315
HIS A 352
ILE A 353
 None
 1.38A 4okbA-3ehfA:
undetectable		 4okbA-3ehfA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3ehf SENSOR KINASE (YOCF
PROTEIN)
(Bacillus
subtilis) 		4 / 6 LEU A 250
LEU A 246
GLU A 249
ILE A 316
 None
 0.86A 4ww7A-3ehfA:
undetectable		 4ww7A-3ehfA:
21.53