SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ehm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 141
THR A 135
PHE A 215
LEU A 132
LEU A 166
 None
 1.22A 1eiiA-3ehmA:
undetectable		 1eiiA-3ehmA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A 277
GLY A 276
GLY A  63
TYR A  64
 None
 0.88A 1eswA-3ehmA:
undetectable		 1eswA-3ehmA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifA-3ehmA:
undetectable		 1kifA-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifB-3ehmA:
undetectable		 1kifB-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifC-3ehmA:
undetectable		 1kifC-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifD-3ehmA:
undetectable		 1kifD-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifE-3ehmA:
undetectable		 1kifE-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifF-3ehmA:
undetectable		 1kifF-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifG-3ehmA:
undetectable		 1kifG-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 1kifH-3ehmA:
undetectable		 1kifH-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 104
GLY A  24
ILE A 119
ALA A 108
GLU A 116
 None
 0.98A 1mrgA-3ehmA:
undetectable		 1mrgA-3ehmA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 208
ASP A  54
ASN A 256
GLU A 449
 None
 1.27A 1rjdA-3ehmA:
undetectable		 1rjdA-3ehmA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 208
ASP A  54
ASN A 256
GLU A 449
 None
 1.26A 1rjdB-3ehmA:
undetectable		 1rjdB-3ehmA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A 208
ASP A  54
ASN A 256
GLU A 449
 None
 1.28A 1rjdC-3ehmA:
undetectable		 1rjdC-3ehmA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 467
PHE A  73
ASN A  78
ALA A  77
 None
 1.14A 1rqpC-3ehmA:
undetectable		 1rqpC-3ehmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 467
PHE A  73
ASN A  78
ALA A  77
 None
 1.14A 1rqpA-3ehmA:
undetectable		 1rqpA-3ehmA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.36A 1ve9A-3ehmA:
undetectable		 1ve9A-3ehmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ARG A  33
SER A 145
TYR A 143
 None
 0.70A 1x70A-3ehmA:
undetectable		 1x70A-3ehmA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 7 SER A 242
ASP A 239
SER A 241
ASN A 197
GLN A 196
 None
 1.47A 2cmlA-3ehmA:
undetectable		 2cmlA-3ehmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 8 SER A 242
ASP A 239
SER A 241
ASN A 197
GLN A 196
 None
 1.50A 2cmlB-3ehmA:
undetectable		 2cmlB-3ehmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 242
ASP A 239
SER A 241
ASN A 197
 None
 0.93A 2cmlC-3ehmA:
undetectable		 2cmlC-3ehmA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.31A 2du8G-3ehmA:
undetectable		 2du8G-3ehmA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 277
TYR A 440
ILE A  62
GLY A 276
 None
 1.32A 2du8J-3ehmA:
undetectable		 2du8J-3ehmA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 467
PHE A  73
ASN A  78
ALA A  77
 None
 1.15A 2v7uA-3ehmA:
undetectable		 2v7uA-3ehmA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 156
THR A 219
GLU A 159
 None
 0.83A 2zifB-3ehmA:
undetectable		 2zifB-3ehmA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 489
MET A 500
PHE A 155
ASN A  87
 None
 1.01A 2zseA-3ehmA:
undetectable		 2zseA-3ehmA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 4 GLY A 271
VAL A 308
GLY A 293
THR A 294
 None
 0.66A 3ib2A-3ehmA:
undetectable		 3ib2A-3ehmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 277
TYR A 281
TYR A 385
PHE A 374
 None
 1.18A 3ku9B-3ehmA:
2.3		 3ku9B-3ehmA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A 366
GLN A 438
ILE A 274
LEU A 441
 None
 1.24A 3ls4L-3ehmA:
undetectable		 3ls4L-3ehmA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 367
GLY A 369
PHE A 374
ALA A 442
GLN A 438
 None
 1.12A 3nvkF-3ehmA:
1.9
3nvkJ-3ehmA:
undetectable		 3nvkF-3ehmA:
20.86
3nvkJ-3ehmA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 367
TYR A 385
PHE A 374
ALA A 442
GLN A 438
 None
 1.22A 3nvkF-3ehmA:
1.9
3nvkJ-3ehmA:
undetectable		 3nvkF-3ehmA:
20.86
3nvkJ-3ehmA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 ASN A  67
ASP A  54
GLU A 449
THR A 452
 None
 1.40A 3p2kC-3ehmA:
undetectable		 3p2kC-3ehmA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_D_SAMD6735_1
(16S RRNA METHYLASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 4 ASN A  67
ASP A  54
GLU A 449
THR A 452
 None
 1.38A 3p2kD-3ehmA:
0.0		 3p2kD-3ehmA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 GLN A 377
TYR A 289
ILE A 274
SER A 373
 None
 1.21A 3peoG-3ehmA:
undetectable		 3peoG-3ehmA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 PHE A 155
PRO A 140
GLY A 509
ILE A 512
PHE A 489
 None
 1.46A 4kotA-3ehmA:
undetectable		 4kotA-3ehmA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A  33
ILE A  37
GLN A  32
ILE A  97
 None
 1.00A 4w5oA-3ehmA:
undetectable		 4w5oA-3ehmA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 104
GLY A  24
ILE A 119
ALA A 108
GLU A 116
 None
 0.94A 4yp2B-3ehmA:
undetectable		 4yp2B-3ehmA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A  33
ILE A  37
GLN A  32
ILE A  97
 None
 0.98A 4z4cA-3ehmA:
undetectable		 4z4cA-3ehmA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A  33
ILE A  37
GLN A  32
ILE A  97
 None
 0.99A 4z4dA-3ehmA:
undetectable		 4z4dA-3ehmA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A 455
SER A  58
PHE A 138
THR A 135
ASN A  92
 None
 1.15A 4z7fC-3ehmA:
2.0		 4z7fC-3ehmA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 104
GLY A  24
ILE A 119
ALA A 108
GLU A 116
 None
 0.95A 5cf9B-3ehmA:
undetectable		 5cf9B-3ehmA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_B_X6XB203_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 9 ASN A 177
GLY A 234
GLY A 235
VAL A 173
ASP A 230
 None
 1.36A 5f8yB-3ehmA:
undetectable		 5f8yB-3ehmA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 462
THR A 273
PRO A 460
LEU A 278
 None
 0.96A 5fxtA-3ehmA:
undetectable		 5fxtA-3ehmA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU A  76
PHE A  65
THR A 268
PHE A 487
 None
 1.18A 5lrbA-3ehmA:
undetectable		 5lrbA-3ehmA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 220
SER A 172
GLN A 158
ARG A 127
LEU A 132
 None
 1.34A 5m50E-3ehmA:
undetectable		 5m50E-3ehmA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 6 MET A 184
ASN A 197
VAL A 195
GLN A 196
 None
 1.15A 5xdhA-3ehmA:
undetectable
5xdhC-3ehmA:
undetectable		 5xdhA-3ehmA:
10.07
5xdhC-3ehmA:
10.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 271
ASN A  60
SER A  58
ALA A 447
 None
 0.96A 5xu8A-3ehmA:
undetectable		 5xu8A-3ehmA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A 277
TYR A  64
ILE A  62
LEU A 462
LEU A 409
 None
 1.31A 5zwrB-3ehmA:
undetectable		 5zwrB-3ehmA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		5 / 9 VAL A 213
HIS A 214
ARG A 212
VAL A 137
ASP A 136
 None
 1.45A 6c2mA-3ehmA:
undetectable		 6c2mA-3ehmA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 5 VAL A 236
LYS A 200
ASN A 203
PRO A 231
 None
 1.42A 6fi4A-3ehmA:
5.3
6fi4B-3ehmA:
undetectable		 6fi4A-3ehmA:
20.72
6fi4B-3ehmA:
1.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 156
ILE A 503
PRO A 504
LEU A 506
 None
 1.21A 6mkeB-3ehmA:
undetectable		 6mkeB-3ehmA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3ehm SUSD HOMOLOG
(Bacteroides
thetaiotaomicron) 		4 / 4 ASP A 156
ILE A 503
PRO A 504
LEU A 506
 None
 1.18A 6mkeA-3ehmA:
undetectable		 6mkeA-3ehmA:
8.64