SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ehq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3ehq OSTEOCLAST-STIMULATI
NG FACTOR 1
(Homo
sapiens) 		3 / 3 LEU A 159
TRP A 112
TYR A 152
 None
 0.98A 3aicA-3ehqA:
undetectable		 3aicA-3ehqA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3ehq OSTEOCLAST-STIMULATI
NG FACTOR 1
(Homo
sapiens) 		4 / 7 SER A  54
TYR A  65
ILE A  39
ASP A  37
 None
 1.21A 3bu1A-3ehqA:
undetectable		 3bu1A-3ehqA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3ehq OSTEOCLAST-STIMULATI
NG FACTOR 1
(Homo
sapiens) 		3 / 3 ASN A 137
ALA A 105
LYS A 138
 None
 0.98A 3runA-3ehqA:
undetectable		 3runA-3ehqA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)		 3ehq OSTEOCLAST-STIMULATI
NG FACTOR 1
(Homo
sapiens) 		5 / 12 ILE A  61
PRO A  62
GLN A  69
ILE A  33
SER A  54
 None
 1.28A 4uroC-3ehqA:
undetectable		 4uroC-3ehqA:
24.81