SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ei8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 THR A 390
PRO A 391
GLY A 392
PHE A  39
 None
 0.88A 1oc3A-3ei8A:
undetectable		 1oc3A-3ei8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 TYR A 364
PRO A 150
PHE A 395
ARG A 404
 None
 1.30A 1oniA-3ei8A:
undetectable
1oniC-3ei8A:
undetectable		 1oniA-3ei8A:
18.10
1oniC-3ei8A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 TYR A 290
VAL A 143
VAL A 235
ILE A 233
 None
 1.00A 1p7rA-3ei8A:
undetectable		 1p7rA-3ei8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 ASN A 208
GLY A 398
ASP A 149
ARG A 182
THR A 211
 None
 1.28A 2f9wA-3ei8A:
undetectable
2f9wB-3ei8A:
undetectable		 2f9wA-3ei8A:
20.32
2f9wB-3ei8A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 GLY A 280
LEU A 135
PHE A 300
THR A 265
 None
 0.97A 2vl2B-3ei8A:
undetectable		 2vl2B-3ei8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 7 THR A 390
PRO A 391
GLY A 392
PHE A  39
 None
 0.88A 2vl2B-3ei8A:
undetectable		 2vl2B-3ei8A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 ALA A 241
TYR A 243
ALA A 266
TYR A 240
 GOL  A 436 ( 3.7A)
None
GOL  A 436 (-3.4A)
PLP  A 433 (-4.5A)
 1.29A 2wlkA-3ei8A:
undetectable
2wlkB-3ei8A:
undetectable		 2wlkA-3ei8A:
22.73
2wlkB-3ei8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 PHE A 274
SER A 267
TRP A 281
ALA A 311
ALA A 319
 None
PLP  A 433 (-2.5A)
None
None
None
 1.32A 2wscB-3ei8A:
0.0		 2wscB-3ei8A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_B_PQNB1774_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 PHE A 274
SER A 267
TRP A 281
ALA A 311
ALA A 319
 None
PLP  A 433 (-2.5A)
None
None
None
 1.33A 2wseB-3ei8A:
0.0		 2wseB-3ei8A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_B_PQNB1773_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 9 PHE A 274
SER A 267
TRP A 281
ALA A 311
ALA A 319
 None
PLP  A 433 (-2.5A)
None
None
None
 1.31A 2wsfB-3ei8A:
0.0		 2wsfB-3ei8A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 8 ASN A 270
GLY A  64
SER A 406
THR A 342
 None
 0.97A 2yoeB-3ei8A:
undetectable
2yoeC-3ei8A:
undetectable		 2yoeB-3ei8A:
21.75
2yoeC-3ei8A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 VAL A  58
ARG A  45
ILE A  63
THR A 385
 None
 0.79A 3cl9A-3ei8A:
undetectable		 3cl9A-3ei8A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 MET A 244
ALA A 215
VAL A 224
ILE A 252
THR A 221
 None
 1.21A 3dl9A-3ei8A:
undetectable		 3dl9A-3ei8A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 SER A 373
GLN A 372
PHE A 369
 None
 0.69A 3g4lC-3ei8A:
undetectable		 3g4lC-3ei8A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 ILE A  70
PHE A 274
ILE A  74
THR A  66
 None
 0.84A 3ia4A-3ei8A:
undetectable		 3ia4A-3ei8A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 6 PHE A 349
PHE A 421
TYR A 425
VAL A 403
 None
 1.29A 3lb3A-3ei8A:
undetectable		 3lb3A-3ei8A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 PRO A 363
SER A 406
ASN A 209
 None
None
PLP  A 433 (-3.6A)
 0.65A 3lslG-3ei8A:
0.8		 3lslG-3ei8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 PHE A 274
SER A 267
TRP A 281
ALA A 311
ALA A 319
 None
PLP  A 433 (-2.5A)
None
None
None
 1.30A 3lw5B-3ei8A:
undetectable		 3lw5B-3ei8A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 5 PHE A 204
ILE A 132
ASN A 361
PHE A 203
 None
 1.21A 3octA-3ei8A:
undetectable		 3octA-3ei8A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 PHE A 203
SER A 158
SER A 159
 None
 1.02A 3ufgB-3ei8A:
undetectable		 3ufgB-3ei8A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 TYR A 354
HIS A 429
VAL A 377
ILE A 381
PHE A 349
 None
 1.29A 4drhA-3ei8A:
undetectable		 4drhA-3ei8A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 9 GLU A 326
GLY A 327
GLU A  68
GLY A 273
TYR A 271
 None
None
None
None
GOL  A 436 (-4.6A)
 1.48A 4fimA-3ei8A:
undetectable		 4fimA-3ei8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 ALA A 239
THR A 282
GLY A 280
GLY A 127
ALA A 128
 PLP  A 433 ( 4.3A)
None
None
PLP  A 433 (-3.3A)
PLP  A 433 (-3.7A)
 0.82A 4qvpK-3ei8A:
undetectable
4qvpL-3ei8A:
undetectable		 4qvpK-3ei8A:
18.76
4qvpL-3ei8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 10 ALA A 239
THR A 282
GLY A 280
GLY A 127
ALA A 128
 PLP  A 433 ( 4.3A)
None
None
PLP  A 433 (-3.3A)
PLP  A 433 (-3.7A)
 0.82A 4qvpY-3ei8A:
undetectable
4qvpZ-3ei8A:
undetectable		 4qvpY-3ei8A:
18.76
4qvpZ-3ei8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 SER A 238
ASP A 237
GLU A 264
PRO A 363
TYR A 271
 GOL  A 436 (-3.4A)
PLP  A 433 (-3.1A)
GOL  A 436 (-3.3A)
None
GOL  A 436 (-4.6A)
 1.30A 5jh7B-3ei8A:
undetectable		 5jh7B-3ei8A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 11 SER A 238
ASP A 237
GLU A 264
PRO A 363
TYR A 271
 GOL  A 436 (-3.4A)
PLP  A 433 (-3.1A)
GOL  A 436 (-3.3A)
None
GOL  A 436 (-4.6A)
 1.36A 5jh7D-3ei8A:
undetectable		 5jh7D-3ei8A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		3 / 3 THR A 165
SER A 159
ASP A 200
 None
 0.77A 5kvaA-3ei8A:
3.0		 5kvaA-3ei8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		5 / 12 ALA A 330
PHE A 274
GLN A 316
LEU A 279
VAL A 277
 None
None
GOL  A 435 ( 4.6A)
None
None
 1.22A 5tudD-3ei8A:
undetectable		 5tudD-3ei8A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 LEU A 279
GLY A 280
SER A 267
SER A 269
 None
None
PLP  A 433 (-2.5A)
PLP  A 433 (-2.6A)
 1.36A 5uunA-3ei8A:
undetectable		 5uunA-3ei8A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Arabidopsis
thaliana) 		4 / 4 LEU A 279
GLY A 280
SER A 267
SER A 269
 None
None
PLP  A 433 (-2.5A)
PLP  A 433 (-2.6A)
 1.35A 5uunB-3ei8A:
undetectable		 5uunB-3ei8A:
24.58