SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 11 ASN C 276
TYR C 278
LEU C 302
ILE C 279
ASP C 280
 None
 1.37A 1t6zB-3eiqC:
undetectable		 1t6zB-3eiqC:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 11 ILE C 396
LEU C 387
ARG C 403
GLY C 404
LYS C 402
 None
 1.37A 2bxmA-3eiqC:
undetectable		 2bxmA-3eiqC:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 6 SER C 206
LEU C 207
ASP C 246
GLU C 165
 None
 1.21A 2j2pE-3eiqC:
undetectable
2j2pF-3eiqC:
undetectable		 2j2pE-3eiqC:
20.91
2j2pF-3eiqC:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 12 THR C 277
ASN C 276
VAL C 269
GLY C 270
ALA C 266
 None
 1.13A 2x2iC-3eiqC:
undetectable		 2x2iC-3eiqC:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 12 ALA C 268
GLY C 272
LEU C 223
SER C 224
LEU C 243
 None
 1.37A 3bxoA-3eiqC:
undetectable		 3bxoA-3eiqC:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 11 LEU C 209
ALA C 257
LEU C 247
LEU C 243
LEU C 252
 None
 1.44A 5hyrB-3eiqC:
undetectable		 5hyrB-3eiqC:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 12 GLU C 217
LEU C 209
PHE C 264
ARG C 267
LEU C 223
 None
 1.31A 5nd4B-3eiqC:
undetectable		 5nd4B-3eiqC:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OWR_A_1N1A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 8 ALA C 268
ILE C 265
ASP C 241
VAL C 184
 None
 0.64A 5owrA-3eiqC:
undetectable		 5owrA-3eiqC:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 4 GLU C 165
THR C 169
THR C 219
LEU C 209
 None
 1.43A 5v96A-3eiqC:
undetectable		 5v96A-3eiqC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 4 GLU C 165
THR C 169
THR C 219
LEU C 209
 None
 1.44A 5v96B-3eiqC:
undetectable		 5v96B-3eiqC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 4 GLU C 165
THR C 169
THR C 219
LEU C 209
 None
 1.45A 5v96C-3eiqC:
undetectable		 5v96C-3eiqC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		4 / 4 GLU C 165
THR C 169
THR C 219
LEU C 209
 None
 1.45A 5v96D-3eiqC:
undetectable		 5v96D-3eiqC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 10 ILE C 273
LEU C 223
ASN C 182
LEU C 188
ALA C 185
 None
 1.23A 5y7pB-3eiqC:
undetectable		 5y7pB-3eiqC:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 10 ILE C 273
LEU C 223
ASN C 182
LEU C 188
ALA C 185
 None
 1.25A 5y7pD-3eiqC:
undetectable		 5y7pD-3eiqC:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 9 VAL C 200
VAL C 230
LEU C 168
LEU C 191
VAL C 184
 None
 1.32A 6czmA-3eiqC:
undetectable
6czmB-3eiqC:
undetectable		 6czmA-3eiqC:
23.19
6czmB-3eiqC:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 9 VAL C 200
VAL C 230
LEU C 168
LEU C 191
VAL C 184
 None
 1.28A 6czmB-3eiqC:
undetectable
6czmC-3eiqC:
undetectable		 6czmB-3eiqC:
23.19
6czmC-3eiqC:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 9 VAL C 200
VAL C 230
LEU C 168
LEU C 191
VAL C 184
 None
 1.28A 6czmD-3eiqC:
undetectable
6czmE-3eiqC:
undetectable		 6czmD-3eiqC:
23.19
6czmE-3eiqC:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3eiq PROGRAMMED CELL
DEATH PROTEIN 4
(Mus
musculus) 		5 / 10 VAL C 200
VAL C 230
LEU C 168
LEU C 191
VAL C 184
 None
 1.30A 6czmE-3eiqC:
undetectable
6czmF-3eiqC:
undetectable		 6czmE-3eiqC:
23.19
6czmF-3eiqC:
23.19