SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eix'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 11 ALA A 122
LEU A  60
LEU A 134
LEU A 109
SER A 113
 None
 1.05A 1h9zA-3eixA:
undetectable		 1h9zA-3eixA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 11 ALA A 122
LEU A  60
LEU A 134
LEU A 109
SER A 113
 None
 1.01A 1ha2A-3eixA:
undetectable		 1ha2A-3eixA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 11 PHE A 190
ILE A 188
ASN A 182
GLY A 223
PHE A 224
 None
 1.30A 1ju6A-3eixA:
undetectable		 1ju6A-3eixA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 12 GLY A 205
GLN A 246
ILE A 296
PHE A 274
LEU A 277
 None
 1.34A 1m2zD-3eixA:
undetectable		 1m2zD-3eixA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 11 LEU A 134
ASP A 118
ILE A  78
ALA A 122
ILE A 120
 None
 1.12A 2idwA-3eixA:
undetectable		 2idwA-3eixA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 12 ALA A  54
LEU A 141
ILE A  39
SER A  37
ILE A  57
 None
 1.48A 3lbdA-3eixA:
undetectable		 3lbdA-3eixA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_A_P77A203_1
(PROTEIN S100-A4)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 10 ASP A 147
SER A 124
ASP A 149
SER A 156
PHE A 157
 None
 1.26A 3m0wA-3eixA:
undetectable
3m0wB-3eixA:
0.5
3m0wI-3eixA:
0.5
3m0wJ-3eixA:
0.5		 3m0wA-3eixA:
17.29
3m0wB-3eixA:
17.29
3m0wI-3eixA:
17.29
3m0wJ-3eixA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 10 ASP A 149
SER A 156
PHE A 157
ASP A 147
SER A 124
 None
 1.27A 3m0wE-3eixA:
undetectable
3m0wF-3eixA:
undetectable
3m0wG-3eixA:
undetectable
3m0wH-3eixA:
0.5		 3m0wE-3eixA:
17.29
3m0wF-3eixA:
17.29
3m0wG-3eixA:
17.29
3m0wH-3eixA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		6 / 12 GLY A 205
ASP A 280
LEU A 207
GLN A 246
ILE A 262
LEU A 197
 None
 1.27A 4fr0A-3eixA:
2.2		 4fr0A-3eixA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 12 ILE A 120
GLU A  44
ALA A  79
SER A 156
ILE A 160
 None
 1.12A 5igvA-3eixA:
undetectable		 5igvA-3eixA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		4 / 4 GLY A  77
LEU A 115
VAL A 101
GLU A 111
 None
 1.27A 5yw0A-3eixA:
undetectable		 5yw0A-3eixA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		4 / 9 ASP A  81
VAL A 301
SER A 310
ASP A 300
 None
 0.89A 6c2mD-3eixA:
undetectable		 6c2mD-3eixA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 11 ASN A 135
THR A 140
THR A  47
GLY A  46
GLU A  44
 None
 1.06A 6mb5A-3eixA:
undetectable		 6mb5A-3eixA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 3eix HTSA PROTEIN
(Staphylococcus
aureus) 		5 / 10 ASN A 131
THR A 140
THR A  47
GLY A  46
GLU A  44
 None
 1.36A 6mb7A-3eixA:
0.0		 6mb7A-3eixA:
14.08