SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M4G_A_RIOA500_0 (AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE)	3eiz	INORGANIC PYROPHOSPHATASE (Burkholderia pseudomallei)	5 / 9	ASP A 103 ASP A 71 GLU A 21 ARG A 44 ASP A 68	None	1.33A	1m4gA-3eizA: 0.0	1m4gA-3eizA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WOP_A_FFOA2887_1 (AMINOMETHYLTRANSFERA SE)	3eiz	INORGANIC PYROPHOSPHATASE (Burkholderia pseudomallei)	3 / 3	ASP A 66 GLU A 21 ARG A 44	None	0.76A	1wopA-3eizA: undetectable	1wopA-3eizA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	3eiz	INORGANIC PYROPHOSPHATASE (Burkholderia pseudomallei)	5 / 12	GLY A 57 VAL A 86 ALA A 33 ASP A 68 ASN A 55	None	1.14A	3qowA-3eizA: undetectable	3qowA-3eizA: 19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_F_SAMF301_0 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3eiz	INORGANIC PYROPHOSPHATASE (Burkholderia pseudomallei)	5 / 12	ASP A 34 PRO A 69 GLY A 57 GLU A 21 TYR A 56	None	1.13A	5hfjF-3eizA: undetectable	5hfjF-3eizA: 23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	3eiz	INORGANIC PYROPHOSPHATASE (Burkholderia pseudomallei)	3 / 3	THR A -10 MET A -12 HIS A -13	None	0.98A	5uunA-3eizA: undetectable	5uunA-3eizA: 20.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M4G_A_RIOA500_0","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","3eiz","INORGANIC PYROPHOSPHATASE","Burkholderia pseudomallei",5,"ASP A 103;ASP A  71;GLU A  21;ARG A  44;ASP A  68","None","1.33A","1m4gA-3eizA:0.0","1m4gA-3eizA:20.44"],["1WOP_A_FFOA2887_1","AMINOMETHYLTRANSFERASE","3eiz","INORGANIC PYROPHOSPHATASE","Burkholderia pseudomallei",3,"ASP A  66;GLU A  21;ARG A  44","None","0.76A","1wopA-3eizA:undetectable","1wopA-3eizA:18.84"],["3QOW_A_SAMA417_0","HISTONE-LYSINE N-METHYLTRANSFERASE","3eiz","INORGANIC PYROPHOSPHATASE","Burkholderia pseudomallei",5,"GLY A  57;VAL A  86;ALA A  33;ASP A  68;ASN A  55","None","1.14A","3qowA-3eizA:undetectable","3qowA-3eizA:19.25"],["5HFJ_F_SAMF301_0","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3eiz","INORGANIC PYROPHOSPHATASE","Burkholderia pseudomallei",5,"ASP A  34;PRO A  69;GLY A  57;GLU A  21;TYR A  56","None","1.13A","5hfjF-3eizA:undetectable","5hfjF-3eizA:23.98"],["5UUN_A_ACTA305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","3eiz","INORGANIC PYROPHOSPHATASE","Burkholderia pseudomallei",3,"THR A -10;MET A -12;HIS A -13","None","0.98A","5uunA-3eizA:undetectable","5uunA-3eizA:20.21"]]