SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ejf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
5 / 12 ASP A 117
VAL A 116
CYH A  89
VAL A  79
TYR A  64
None
0.97A 2g70A-3ejfA:
undetectable
2g70A-3ejfA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
5 / 12 ASP A 117
VAL A 116
CYH A  89
VAL A  79
TYR A  64
None
0.94A 2g70B-3ejfA:
undetectable
2g70B-3ejfA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
5 / 12 ASP A 117
VAL A 116
CYH A  89
VAL A  79
TYR A  64
None
0.98A 2g72A-3ejfA:
undetectable
2g72A-3ejfA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
3 / 3 ALA A  38
GLY A 130
SER A 139
None
0.45A 2ivuA-3ejfA:
undetectable
2ivuA-3ejfA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMQ_A_BEZA3_0
(PROTEIN NDRG2)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
4 / 7 TYR A 122
GLN A  88
PHE A  30
ARG A 153
None
1.10A 2qmqA-3ejfA:
undetectable
2qmqA-3ejfA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
5 / 12 HIS A  45
VAL A  49
PHE A 157
VAL A  90
VAL A 123
None
1.14A 3czvA-3ejfA:
undetectable
3czvB-3ejfA:
undetectable
3czvA-3ejfA:
17.76
3czvB-3ejfA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
4 / 4 THR A 151
ARG A 153
GLU A  11
VAL A 120
None
1.23A 4odoC-3ejfA:
undetectable
4odoC-3ejfA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)
3ejf NON-STRUCTURAL
PROTEIN 3

(Avian
coronavirus)
4 / 7 LEU A 127
PRO A 125
ILE A  53
MET A  43
None
0.93A 5fxtA-3ejfA:
undetectable
5fxtA-3ejfA:
18.01