SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ejv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ETA_1_T441128_1 (TRANSTHYRETIN)	3ejv	UNCHARACTERIZED PROTEIN WITH CYSTATIN-LIKE FOLD (Novosphingobium aromaticivorans)	4 / 5	LEU A 95 GLU A 6 ALA A 93 LEU A 135	None	1.19A	1eta1-3ejvA: undetectable	1eta1-3ejvA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZR_B_CDXB901_2 (DNA TOPOISOMERASE II)	3ejv	UNCHARACTERIZED PROTEIN WITH CYSTATIN-LIKE FOLD (Novosphingobium aromaticivorans)	4 / 7	THR A 17 ASN A 11 LEU A 31 GLN A 15	None	0.96A	1qzrB-3ejvA: undetectable	1qzrB-3ejvA: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NOA_A_3TCA302_1 (DEOXYCYTIDINE KINASE)	3ejv	UNCHARACTERIZED PROTEIN WITH CYSTATIN-LIKE FOLD (Novosphingobium aromaticivorans)	5 / 12	ILE A 151 MET A 28 TYR A 16 PHE A 32 ALA A 36	UNL A 200 (-4.4A) UNL A 200 (-2.7A) UNL A 200 (-4.3A) None None	1.22A	2noaA-3ejvA: undetectable	2noaA-3ejvA: 22.67