SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ek5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 5 LEU A  79
VAL A  82
LEU A  86
GLN A  89
 None
 0.72A 1fbmE-3ek5A:
undetectable		 1fbmE-3ek5A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 4 ILE A  31
LEU A  34
VAL A  38
ALA A  46
 None
 0.62A 1mz9A-3ek5A:
undetectable		 1mz9A-3ek5A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 5 ILE A  31
LEU A  34
VAL A  38
ALA A  46
 None
 0.64A 1mz9C-3ek5A:
undetectable		 1mz9C-3ek5A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 5 TYR A 186
ILE A 151
ARG A 239
GLY A 238
 None
 1.36A 2du8G-3ek5A:
2.7		 2du8G-3ek5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 5 TYR A 186
ILE A 151
ARG A 239
GLY A 238
 None
 1.37A 2du8J-3ek5A:
2.9		 2du8J-3ek5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 12 LEU A  18
GLY A  53
GLY A  15
ALA A  80
THR A  81
 None
 1.11A 3dh0B-3ek5A:
3.8		 3dh0B-3ek5A:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 7 GLY A  54
ASN A  84
GLY A 134
THR A 135
 None
 0.74A 3tajA-3ek5A:
undetectable		 3tajA-3ek5A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 12 GLY A 233
ARG A 180
GLY A 216
ASP A 182
GLN A 231
 None
 1.17A 3tkaA-3ek5A:
3.6		 3tkaA-3ek5A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 11 THR A 142
ALA A 146
LEU A 158
VAL A  38
ILE A 130
 None
 1.49A 4claA-3ek5A:
undetectable		 4claA-3ek5A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 4 LEU A 148
ILE A 153
GLY A 145
PHE A 131
 None
 1.09A 4dc3A-3ek5A:
2.2		 4dc3A-3ek5A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		4 / 6 LEU A 159
LEU A 235
MET A 197
VAL A 189
 None
 1.07A 4okbA-3ek5A:
undetectable		 4okbA-3ek5A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 10 ALA A 150
LEU A 159
LEU A 210
LEU A 204
ALA A 205
 None
 1.17A 4zbrA-3ek5A:
undetectable		 4zbrA-3ek5A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		3 / 3 ASP A  23
ASN A  56
PHE A  58
 None
 0.76A 5dsgB-3ek5A:
undetectable		 5dsgB-3ek5A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 12 LEU A   4
ALA A  44
ILE A 130
ILE A   9
LEU A  34
 None
 0.99A 5h8tA-3ek5A:
undetectable		 5h8tA-3ek5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 12 LEU A   4
ALA A  44
ILE A 130
ILE A   9
LEU A  34
 None
 0.92A 5hbsA-3ek5A:
undetectable		 5hbsA-3ek5A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 3ek5 URIDYLATE KINASE
(Xanthomonas
campestris) 		5 / 12 ALA A 161
GLY A 216
LEU A 223
VAL A 222
LEU A  50
 None
 1.21A 5w7pA-3ek5A:
3.2		 5w7pA-3ek5A:
20.61