SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ek9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		3 / 4 VAL A 106
TRP A 131
TRP A  91
 None
 1.34A 1gmkC-3ek9A:
undetectable
1gmkD-3ek9A:
undetectable		 1gmkC-3ek9A:
11.65
1gmkD-3ek9A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		4 / 6 SER A  74
ASN A  56
ILE A  57
ASP A  76
 None
 1.04A 1yc2A-3ek9A:
undetectable		 1yc2A-3ek9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA156_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		4 / 7 THR A 110
TRP A 131
MET A 173
LEU A 171
 None
 1.37A 2rezA-3ek9A:
undetectable		 2rezA-3ek9A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA301_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		4 / 6 TRP A  91
ILE A 214
TRP A  48
VAL A  78
 None
 1.25A 3deuA-3ek9A:
undetectable		 3deuA-3ek9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		5 / 10 VAL A 169
LEU A 167
GLY A 107
VAL A 203
TRP A 133
 None
 1.16A 3ls4H-3ek9A:
undetectable		 3ls4H-3ek9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		4 / 7 LEU A 167
VAL A  78
TRP A  95
ILE A  93
 None
 0.90A 3wsjB-3ek9A:
undetectable		 3wsjB-3ek9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3ek9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 2
(Mus
musculus) 		5 / 12 GLY A  80
GLY A  47
GLY A  63
ALA A 109
LEU A 115
 None
 0.91A 5c0oF-3ek9A:
undetectable		 5c0oF-3ek9A:
undetectable