SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3eka HYALURONIDASE, PHAGE
ASSOCIATED
(Streptococcus
pyogenes) 		5 / 11 PHE A  49
ALA A  40
GLY A  43
ILE A  55
ASP A  44
 None
 1.11A 4dcmA-3ekaA:
undetectable		 4dcmA-3ekaA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3eka HYALURONIDASE, PHAGE
ASSOCIATED
(Streptococcus
pyogenes) 		3 / 3 ASN A 280
PHE A 286
TYR A 295
 None
 0.85A 4u15A-3ekaA:
undetectable		 4u15A-3ekaA:
20.41