SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eli'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		5 / 12 VAL A  67
SER A  55
VAL A  99
LEU A   4
HIS A 128
 None
 1.31A 2hc4A-3eliA:
undetectable		 2hc4A-3eliA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		5 / 12 ILE A 102
LEU A 112
LEU A  17
THR A  72
VAL A  21
 None
 1.20A 3dcjA-3eliA:
undetectable
3dcjB-3eliA:
undetectable		 3dcjA-3eliA:
22.47
3dcjB-3eliA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.32A 3jx1A-3eliA:
undetectable
3jx1B-3eliA:
undetectable		 3jx1A-3eliA:
15.93
3jx1B-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.35A 3nlyA-3eliA:
undetectable
3nlyB-3eliA:
undetectable		 3nlyA-3eliA:
15.93
3nlyB-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.34A 3rqlA-3eliA:
undetectable
3rqlB-3eliA:
undetectable		 3rqlA-3eliA:
15.93
3rqlB-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 7 PRO A  14
GLY A 109
ALA A 110
ARG A 111
 None
 0.78A 3ur0B-3eliA:
undetectable		 3ur0B-3eliA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.36A 4capA-3eliA:
undetectable
4capB-3eliA:
undetectable		 4capA-3eliA:
15.93
4capB-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.35A 4d32A-3eliA:
undetectable
4d32B-3eliA:
undetectable		 4d32A-3eliA:
15.93
4d32B-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 ASP A  23
GLU A 146
VAL A  12
ALA A  13
 None
 0.96A 4nkvC-3eliA:
undetectable		 4nkvC-3eliA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 5 GLY A  24
ASP A  23
GLU A 142
VAL A  12
 None
 1.09A 4nkvD-3eliA:
undetectable		 4nkvD-3eliA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 6 ASP A  23
GLU A 146
VAL A  12
ALA A  13
 None
 1.00A 4nkxA-3eliA:
undetectable		 4nkxA-3eliA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 TRP A  84
GLU A  96
SER A  97
VAL A  99
 None
 1.33A 4v3yA-3eliA:
undetectable
4v3yB-3eliA:
undetectable		 4v3yA-3eliA:
15.93
4v3yB-3eliA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eli AHA1 DOMAIN PROTEIN
(Ruegeria
pomeroyi) 		4 / 8 SER A  97
VAL A  99
TRP A  84
GLU A  96
 None
 1.35A 5uo7A-3eliA:
undetectable
5uo7B-3eliA:
undetectable		 5uo7A-3eliA:
16.27
5uo7B-3eliA:
16.27