SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3elk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		5 / 12 ILE A  19
LEU A  23
GLY A  30
GLN A  75
ILE A  50
 None
 1.15A 2e7fB-3elkA:
undetectable		 2e7fB-3elkA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		5 / 12 ILE A  19
LEU A  23
GLY A  30
GLN A  75
ILE A  50
 None
 1.23A 2ogyA-3elkA:
undetectable		 2ogyA-3elkA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		5 / 12 ILE A  19
LEU A  23
GLY A  30
GLN A  75
ILE A  50
 None
 1.28A 2ogyB-3elkA:
undetectable		 2ogyB-3elkA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		5 / 12 ILE A  19
LEU A  23
GLY A  30
GLN A  75
ILE A  50
 None
 1.09A 2ycjA-3elkA:
undetectable		 2ycjA-3elkA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		3 / 3 THR A  40
HIS A  92
LEU A  96
 None
 0.79A 5axdA-3elkA:
undetectable		 5axdA-3elkA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3elk PUTATIVE
TRANSCRIPTIONAL
REGULATOR TA0346
(Thermoplasma
acidophilum) 		3 / 3 THR A  40
HIS A  92
LEU A  96
 None
 0.79A 5axdC-3elkA:
undetectable		 5axdC-3elkA:
13.86