SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3elu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		3 / 3 VAL A 132
VAL A 164
TRP A 171
 SAM  A4633 (-3.4A)
None
None
 0.89A 1av2C-3eluA:
undetectable
1av2D-3eluA:
undetectable		 1av2C-3eluA:
8.46
1av2D-3eluA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 11 SER A  54
LEU A 259
LEU A  71
VAL A 257
ILE A  62
 None
 1.36A 1ee2A-3eluA:
4.1		 1ee2A-3eluA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 11 SER A  54
LEU A 259
LEU A  71
VAL A 257
ILE A  62
 None
 1.38A 1ee2B-3eluA:
4.7		 1ee2B-3eluA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
None
 0.63A 1eizA-3eluA:
14.8		 1eizA-3eluA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
 0.28A 1ej0A-3eluA:
14.7		 1ej0A-3eluA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
LEU A 105
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
None
 0.72A 1ej0A-3eluA:
14.7		 1ej0A-3eluA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 9 TYR A 221
ILE A 206
GLY A 204
ILE A 229
GLU A 196
 None
 1.34A 1mrgA-3eluA:
undetectable		 1mrgA-3eluA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 11 THR A 118
ARG A  37
LEU A  44
ILE A  53
ASP A 256
 None
SO4  A4637 (-3.8A)
None
None
None
 1.11A 1t6zA-3eluA:
undetectable		 1t6zA-3eluA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		3 / 3 VAL A 132
VAL A 164
TRP A 171
 SAM  A4633 (-3.4A)
None
None
 0.92A 1w5uC-3eluA:
undetectable
1w5uD-3eluA:
undetectable		 1w5uC-3eluA:
8.46
1w5uD-3eluA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 9 THR A 236
VAL A 183
THR A 161
ILE A 192
VAL A 191
 None
 1.07A 2l8mA-3eluA:
undetectable		 2l8mA-3eluA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
LEU A 105
VAL A 132
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.4A)
None
 0.70A 2nyuA-3eluA:
14.4		 2nyuA-3eluA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 GLY A  81
GLY A  85
TRP A  87
LEU A 105
VAL A 132
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.4A)
None
 0.68A 2nyuB-3eluA:
14.4		 2nyuB-3eluA:
25.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		7 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
THR A 104
LEU A 105
GLU A 111
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
 0.71A 2oxtA-3eluA:
38.9		 2oxtA-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 146
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.7A)
 0.44A 2oxtA-3eluA:
38.9		 2oxtA-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
LEU A 105
GLU A 111
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
 0.83A 2oxtB-3eluA:
38.7		 2oxtB-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
LEU A 105
LYS A 182
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
 0.63A 2oxtB-3eluA:
38.7		 2oxtB-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		7 / 12 GLY A  81
GLY A  83
GLY A  85
THR A 104
LEU A 105
GLU A 111
ILE A 147
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
SAM  A4633 ( 4.2A)
 1.35A 2oxtB-3eluA:
38.7		 2oxtB-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 146
 SAM  A4633 ( 2.7A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.7A)
 0.28A 2oxtB-3eluA:
38.7		 2oxtB-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 146
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.7A)
None
 0.47A 2oxtC-3eluA:
38.5		 2oxtC-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		8 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
GLU A 111
ASP A 146
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
SAM  A4633 (-3.7A)
 0.54A 2oxtC-3eluA:
38.5		 2oxtC-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
ASP A  79
GLY A  81
GLY A  83
GLY A  86
THR A 104
LEU A 105
HIS A 110
GLU A 111
ASP A 146
 SAM  A4633 ( 3.7A)
None
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.7A)
 0.59A 2oxtD-3eluA:
38.8		 2oxtD-3eluA:
49.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.31A 2pxcA-3eluA:
39.7		 2pxcA-3eluA:
54.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LEU A 105
GLU A 111
VAL A 132
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.2A)
 0.42A 2wa2A-3eluA:
32.8		 2wa2A-3eluA:
50.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LEU A 105
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.39A 2wa2B-3eluA:
39.9		 2wa2B-3eluA:
50.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		3 / 3 ARG A  76
GLY A  75
SER A 223
 None
 0.61A 2xctB-3eluA:
undetectable		 2xctB-3eluA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
 SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.1A)
 0.31A 3douA-3eluA:
14.0		 3douA-3eluA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASN A 131
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.00A 3eluA-3eluA:
49.6		 3eluA-3eluA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		12 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASN A 131
VAL A 132
PHE A 133
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.15A 3elwA-3eluA:
44.5		 3elwA-3eluA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASN A 131
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.24A 3embA-3eluA:
42.3		 3embA-3eluA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.20A 3gczA-3eluA:
40.6		 3gczA-3eluA:
55.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.48A 3p97A-3eluA:
39.1		 3p97A-3eluA:
54.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.42A 3p97C-3eluA:
38.9		 3p97C-3eluA:
54.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 146
 SAM  A4633 ( 2.7A)
SAM  A4633 (-3.2A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.7A)
 0.50A 4b17A-3eluA:
10.6		 4b17A-3eluA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 7 THR A 142
VAL A 100
ASP A  79
VAL A  77
 None
 1.01A 4cp4A-3eluA:
undetectable		 4cp4A-3eluA:
21.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.47A 4ctjA-3eluA:
39.3		 4ctjA-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.55A 4ctjC-3eluA:
38.9		 4ctjC-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.42A 4ctkA-3eluA:
39.1		 4ctkA-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.39A 4ctkC-3eluA:
38.9		 4ctkC-3eluA:
51.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  83
THR A 104
LEU A 105
ASN A 131
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
SAM  A4633 (-3.6A)
 0.56A 4f84A-3eluA:
8.0		 4f84A-3eluA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 LEU A 259
VAL A 257
ARG A 264
ALA A  59
ALA A  92
 None
 1.05A 4fiaA-3eluA:
undetectable		 4fiaA-3eluA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 LEU A 259
VAL A 257
ARG A 264
ALA A  59
ALA A  92
 None
 1.05A 4fiaA-3eluA:
undetectable		 4fiaA-3eluA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 7 TYR A 187
VAL A 183
ILE A 206
ILE A 229
 None
 0.80A 4lv9A-3eluA:
undetectable		 4lv9A-3eluA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 7 TYR A 187
VAL A 183
ILE A 206
ILE A 229
 None
 0.84A 4lv9B-3eluA:
undetectable		 4lv9B-3eluA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 ILE A  62
GLY A  85
ILE A 114
SER A  56
LEU A  44
 None
SAM  A4633 ( 4.3A)
None
SAM  A4633 ( 2.7A)
None
 1.12A 4mwzA-3eluA:
8.5		 4mwzA-3eluA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  83
GLY A  85
THR A 104
LEU A 105
THR A 134
 SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-4.5A)
SAM  A4633 (-4.1A)
None
 0.93A 4n49A-3eluA:
16.0		 4n49A-3eluA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		3 / 3 GLN A 284
SER A 130
ASP A 128
 None
 0.93A 4qwpA-3eluA:
undetectable
4qwpB-3eluA:
undetectable		 4qwpA-3eluA:
22.68
4qwpB-3eluA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
LEU A 105
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-4.1A)
None
 0.83A 4uciA-3eluA:
9.5		 4uciA-3eluA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
LEU A 105
LYS A 182
 SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.3A)
SAM  A4633 (-4.1A)
None
 0.82A 4uciB-3eluA:
7.6		 4uciB-3eluA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 7 ALA A  91
ARG A  84
GLY A  83
GLU A 111
 None
SO4  A4637 (-3.8A)
SAM  A4633 (-3.4A)
None
 0.95A 5btdA-3eluA:
undetectable
5btdB-3eluA:
undetectable
5btdC-3eluA:
undetectable		 5btdA-3eluA:
20.16
5btdB-3eluA:
21.26
5btdC-3eluA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 7 ALA A  91
ARG A  84
GLY A  83
GLU A 111
 None
SO4  A4637 (-3.8A)
SAM  A4633 (-3.4A)
None
 0.99A 5btdA-3eluA:
undetectable
5btdC-3eluA:
undetectable
5btdD-3eluA:
undetectable		 5btdA-3eluA:
20.16
5btdC-3eluA:
20.16
5btdD-3eluA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		4 / 6 ALA A  91
ARG A  84
GLY A  83
GLU A 111
 None
SO4  A4637 (-3.8A)
SAM  A4633 (-3.4A)
None
 0.94A 5btgA-3eluA:
undetectable
5btgB-3eluA:
undetectable
5btgC-3eluA:
undetectable		 5btgA-3eluA:
20.16
5btgB-3eluA:
21.26
5btgC-3eluA:
20.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.43A 5e9qA-3eluA:
39.0		 5e9qA-3eluA:
55.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.41A 5e9qC-3eluA:
38.8		 5e9qC-3eluA:
55.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.46A 5ec8A-3eluA:
38.9		 5ec8A-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 SER A  56
GLY A  58
GLY A  83
GLY A  86
THR A 104
GLU A 111
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-4.5A)
None
 1.03A 5ec8A-3eluA:
38.9		 5ec8A-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.48A 5ec8C-3eluA:
38.5		 5ec8C-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.43A 5ehgA-3eluA:
38.9		 5ehgA-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.43A 5ehgC-3eluA:
38.7		 5ehgC-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
 1.11A 5ehgC-3eluA:
38.7		 5ehgC-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.41A 5ehiA-3eluA:
39.3		 5ehiA-3eluA:
51.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.41A 5ehiC-3eluA:
39.0		 5ehiC-3eluA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.43A 5eifA-3eluA:
39.3		 5eifA-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.39A 5eifC-3eluA:
38.9		 5eifC-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.49A 5eiwA-3eluA:
39.0		 5eiwA-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.38A 5eiwC-3eluA:
38.8		 5eiwC-3eluA:
51.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 2.7A)
SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.44A 5ekxA-3eluA:
39.2		 5ekxA-3eluA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		11 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.47A 5ekxB-3eluA:
39.1		 5ekxB-3eluA:
51.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.41A 5ikmA-3eluA:
39.4		 5ikmA-3eluA:
51.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.2A)
 0.41A 5kqrA-3eluA:
39.5		 5kqrA-3eluA:
55.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.48A 5kqsA-3eluA:
39.4		 5kqsA-3eluA:
55.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.2A)
 0.44A 5m5bA-3eluA:
39.8		 5m5bA-3eluA:
58.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.43A 5njvA-3eluA:
39.3		 5njvA-3eluA:
54.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.42A 5njvB-3eluA:
39.6		 5njvB-3eluA:
54.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.63A 5njvC-3eluA:
38.4		 5njvC-3eluA:
54.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.49A 5njvD-3eluA:
38.5		 5njvD-3eluA:
54.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 182
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 ( 4.2A)
None
 0.56A 5vimA-3eluA:
39.3		 5vimA-3eluA:
56.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
VAL A 132
PHE A 133
ILE A 147
LYS A 182
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 ( 4.2A)
None
 0.44A 5vimB-3eluA:
39.4		 5vimB-3eluA:
56.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.72A 5wz1A-3eluA:
39.3		 5wz1A-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 ( 4.2A)
 0.71A 5wz1B-3eluA:
39.3		 5wz1B-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.75A 5wz1C-3eluA:
39.1		 5wz1C-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.74A 5wz1D-3eluA:
39.2		 5wz1D-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.73A 5wz1E-3eluA:
39.1		 5wz1E-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.74A 5wz1F-3eluA:
39.2		 5wz1F-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.72A 5wz1G-3eluA:
39.1		 5wz1G-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
None
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.73A 5wz1H-3eluA:
39.1		 5wz1H-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.42A 5wz2A-3eluA:
39.1		 5wz2A-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.42A 5wz2B-3eluA:
39.3		 5wz2B-3eluA:
53.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
VAL A 132
ASP A 146
ILE A 147
 SAM  A4633 ( 3.7A)
SAM  A4633 (-3.2A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.5A)
SAM  A4633 (-4.5A)
SAM  A4633 (-3.6A)
SAM  A4633 (-3.4A)
SAM  A4633 (-3.7A)
SAM  A4633 ( 4.2A)
 0.44A 5wz2C-3eluA:
39.1		 5wz2C-3eluA:
53.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		3 / 3 LYS A 101
LEU A  78
ARG A  76
 None
 0.94A 5yw0A-3eluA:
undetectable		 5yw0A-3eluA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3elu METHYLTRANSFERASE
(Wesselsbron
virus) 		5 / 12 ILE A 206
LEU A 195
THR A 236
THR A 161
LEU A 165
 None
 1.25A 6b54A-3eluA:
undetectable		 6b54A-3eluA:
20.55