SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3emu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		4 / 6 LEU A 322
LYS A 426
GLN A 428
LEU A 430
 None
 1.10A 3h5gB-3emuA:
undetectable
3h5gC-3emuA:
undetectable		 3h5gB-3emuA:
11.80
3h5gC-3emuA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		4 / 7 LEU A 343
ALA A 404
VAL A 427
ILE A 395
 None
 0.89A 3wsjB-3emuA:
undetectable		 3wsjB-3emuA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		4 / 8 GLN A 443
PHE A 440
ILE A 407
VAL A 345
 None
 1.00A 4dx7B-3emuA:
undetectable		 4dx7B-3emuA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		5 / 12 LEU A 372
LEU A 444
ALA A 406
ILE A 376
LEU A 360
 None
 1.12A 5h8tA-3emuA:
undetectable		 5h8tA-3emuA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		5 / 9 LEU A 322
LEU A 412
ILE A 434
GLN A 443
LEU A 372
 None
 1.44A 5ljdA-3emuA:
undetectable		 5ljdA-3emuA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3emu LEUCINE RICH REPEAT
AND PHOSPHATASE
DOMAIN CONTAINING
PROTEIN
(Entamoeba
histolytica) 		5 / 12 LEU A 372
LEU A 444
ALA A 406
ILE A 376
LEU A 360
 None
 1.13A 5ljeA-3emuA:
undetectable		 5ljeA-3emuA:
20.12