SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3emv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
LEU A 139
None
1.03A 1dhfB-3emvA:
undetectable
1dhfB-3emvA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ILE A  74
GLY A  66
GLY A  68
SER A  69
ALA A  73
None
0.90A 1i9gA-3emvA:
undetectable
1i9gA-3emvA:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 10 ARG A  89
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.36A 1jdvA-3emvA:
32.0
1jdvD-3emvA:
31.9
1jdvA-3emvA:
30.08
1jdvD-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 10 ARG A  89
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.34A 1jdvB-3emvA:
31.9
1jdvC-3emvA:
32.4
1jdvB-3emvA:
30.08
1jdvC-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 10 ARG A  89
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.36A 1jdvA-3emvA:
32.0
1jdvD-3emvA:
31.9
1jdvA-3emvA:
30.08
1jdvD-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 12 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 1jdvE-3emvA:
31.9
1jdvF-3emvA:
32.4
1jdvE-3emvA:
30.08
1jdvF-3emvA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.42A 1odiA-3emvA:
25.5
1odiA-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.49A 1odiB-3emvA:
33.4
1odiB-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.42A 1odiC-3emvA:
33.8
1odiC-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.48A 1odiD-3emvA:
33.8
1odiD-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.44A 1odiE-3emvA:
33.9
1odiE-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 ARG A  89
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.43A 1odiF-3emvA:
33.7
1odiF-3emvA:
28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
SER A  92
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.39A 1pk7A-3emvA:
32.2
1pk7A-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 8 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.24A 1pk7B-3emvA:
32.2
1pk7B-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 10 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.36A 1pk7C-3emvA:
32.1
1pk7C-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.23A 1pk7C-3emvA:
32.1
1pk7C-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 10 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.32A 1pk9A-3emvA:
32.3
1pk9A-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 10 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.08A 1pk9A-3emvA:
32.3
1pk9A-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
SER A  92
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.23A 1pk9B-3emvA:
32.4
1pk9B-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 GLY A  94
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.33A 1pk9B-3emvA:
32.4
1pk9B-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.35A 1pk9C-3emvA:
31.8
1pk9C-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 11 GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.14A 1pk9C-3emvA:
31.8
1pk9C-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
SER A  92
GLY A  94
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.30A 1pw7A-3emvA:
32.1
1pw7A-3emvA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 9 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.33A 1pw7B-3emvA:
32.3
1pw7B-3emvA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 SER A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.38A 1pw7C-3emvA:
32.1
1pw7C-3emvA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.08A 1pw7C-3emvA:
32.1
1pw7C-3emvA:
29.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 VAL A  20
VAL A  22
GLU A  52
LEU A  11
ILE A   9
None
1.44A 1t6zB-3emvA:
undetectable
1t6zB-3emvA:
22.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.35A 1vhwA-3emvA:
33.0
1vhwD-3emvA:
33.0
1vhwA-3emvA:
30.08
1vhwD-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
SER A  92
GLY A  94
VAL A 182
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.37A 1vhwB-3emvA:
32.7
1vhwF-3emvA:
32.6
1vhwB-3emvA:
30.08
1vhwF-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 1vhwC-3emvA:
33.1
1vhwE-3emvA:
32.9
1vhwC-3emvA:
30.08
1vhwE-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.32A 1vhwA-3emvA:
33.0
1vhwD-3emvA:
33.0
1vhwA-3emvA:
30.08
1vhwD-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 1vhwC-3emvA:
33.1
1vhwE-3emvA:
32.9
1vhwC-3emvA:
30.08
1vhwE-3emvA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 10 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.37A 1vhwB-3emvA:
32.7
1vhwF-3emvA:
32.6
1vhwB-3emvA:
30.08
1vhwF-3emvA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 1z35A-3emvA:
33.2
1z35A-3emvA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 1z37A-3emvA:
33.3
1z37A-3emvA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 11 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.47A 2ac7A-3emvA:
31.3
2ac7B-3emvA:
31.3
2ac7A-3emvA:
26.74
2ac7B-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
0.89A 2ac7A-3emvA:
31.3
2ac7B-3emvA:
31.3
2ac7A-3emvA:
26.74
2ac7B-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 11 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.47A 2ac7A-3emvA:
31.3
2ac7B-3emvA:
31.3
2ac7A-3emvA:
26.74
2ac7B-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
0.90A 2ac7A-3emvA:
31.3
2ac7B-3emvA:
31.3
2ac7A-3emvA:
26.74
2ac7B-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZQ_A_PCFA954_0
(CATECHOL
1,2-DIOXYGENASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 LEU A 222
GLU A 228
LEU A  21
GLU A 236
LEU A 146
None
1.35A 2azqA-3emvA:
undetectable
2azqA-3emvA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 LEU A 139
VAL A 135
VAL A  19
ILE A  87
VAL A  86
None
1.19A 2l8mA-3emvA:
undetectable
2l8mA-3emvA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
LEU A 139
None
1.13A 2w3bA-3emvA:
undetectable
2w3bA-3emvA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ILE A  74
GLY A  66
GLY A  68
SER A  69
ALA A  73
None
0.90A 2yvlA-3emvA:
undetectable
2yvlA-3emvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
SER A 234
LEU A 139
None
1.10A 3k2hA-3emvA:
undetectable
3k2hA-3emvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
ILE A  88
SER A 234
LEU A 139
None
1.07A 3k2hB-3emvA:
undetectable
3k2hB-3emvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
SER A 234
None
0.95A 3nrrA-3emvA:
undetectable
3nrrA-3emvA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
SER A 234
None
0.95A 3nrrB-3emvA:
undetectable
3nrrB-3emvA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
3 / 3 LEU A  35
ARG A 226
ASN A 221
None
0.66A 3qxvD-3emvA:
undetectable
3qxvD-3emvA:
17.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
SER A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.54A 3u40A-3emvA:
32.1
3u40F-3emvA:
31.6
3u40A-3emvA:
30.97
3u40F-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
SER A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.49A 3u40B-3emvA:
31.5
3u40C-3emvA:
31.5
3u40B-3emvA:
30.97
3u40C-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 12 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.39A 3u40B-3emvA:
31.5
3u40C-3emvA:
31.5
3u40B-3emvA:
30.97
3u40C-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.37A 3u40D-3emvA:
32.1
3u40E-3emvA:
31.4
3u40D-3emvA:
30.97
3u40E-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 12 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.42A 3u40D-3emvA:
32.1
3u40E-3emvA:
31.4
3u40D-3emvA:
30.97
3u40E-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
SER A  92
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.54A 3u40A-3emvA:
32.1
3u40F-3emvA:
31.6
3u40A-3emvA:
30.97
3u40F-3emvA:
30.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 10 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
1.06A 3u40A-3emvA:
32.1
3u40F-3emvA:
31.6
3u40A-3emvA:
30.97
3u40F-3emvA:
30.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
3 / 3 PHE A  76
CYH A  72
HIS A  65
None
1.35A 3u9fL-3emvA:
undetectable
3u9fL-3emvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 11 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.47A 3uawA-3emvA:
32.8
3uawA-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 11 VAL A 182
GLU A 183
MET A 184
GLU A 185
ASP A 207
None
0.88A 3uawA-3emvA:
32.8
3uawA-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.46A 3uayA-3emvA:
32.6
3uayA-3emvA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.43A 4d9hA-3emvA:
31.9
4d9hA-3emvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 9 SER A  92
GLY A  94
VAL A 182
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
0.46A 4da6A-3emvA:
31.4
4da6A-3emvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 ARG A  89
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.39A 4da7A-3emvA:
31.5
4da7A-3emvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 11 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.44A 4danA-3emvA:
31.5
4danA-3emvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 12 ARG A  89
SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
None
0.42A 4danA-3emvA:
31.5
4danB-3emvA:
31.5
4danA-3emvA:
24.00
4danB-3emvA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 VAL A 148
GLY A  91
ILE A 106
ILE A 108
SER A 234
None
SO4  A 254 (-3.4A)
None
None
None
0.88A 4iv0A-3emvA:
undetectable
4iv0A-3emvA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
LEU A 139
None
1.01A 4kebB-3emvA:
undetectable
4kebB-3emvA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 ALA A 112
PHE A 204
THR A 200
ILE A  88
LEU A 139
None
1.03A 4m6kA-3emvA:
undetectable
4m6kA-3emvA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 VAL A 148
GLY A  91
ILE A 106
ILE A 108
SER A 234
None
SO4  A 254 (-3.4A)
None
None
None
0.90A 4mwzB-3emvA:
undetectable
4mwzB-3emvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
4 / 8 ILE A 108
LEU A  21
LEU A 235
ILE A 233
None
0.94A 4xtaB-3emvA:
undetectable
4xtaB-3emvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 ARG A  89
SER A  92
GLY A  94
VAL A 182
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
SO4  A 254 (-3.2A)
None
None
None
None
0.31A 5i3cA-3emvA:
32.9
5i3cA-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 10 SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.38A 5i3cB-3emvA:
32.6
5i3cB-3emvA:
29.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 11 SER A  92
GLY A  94
VAL A 182
GLU A 183
MET A 184
GLU A 185
SO4  A 254 (-3.2A)
None
None
None
None
None
0.34A 5i3cC-3emvA:
32.7
5i3cC-3emvA:
29.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
6 / 9 VAL A  67
GLY A  94
VAL A 182
GLU A 183
MET A 184
ASP A 207
None
1.26A 5zncA-3emvA:
42.4
5zncA-3emvA:
81.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZNC_A_QI9A301_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
7 / 9 VAL A  67
SER A  92
GLY A  94
TYR A 161
VAL A 182
GLU A 183
MET A 184
None
SO4  A 254 (-3.2A)
None
None
None
None
None
0.19A 5zncA-3emvA:
42.4
5zncA-3emvA:
81.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
8 / 9 VAL A  67
GLY A  94
TYR A 161
VAL A 182
GLU A 183
MET A 184
GLY A 208
PRO A 210
None
0.56A 5zniA-3emvA:
42.1
5zniA-3emvA:
47.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
5 / 12 HIS A  65
PHE A  76
GLY A 202
ALA A 112
ILE A 203
None
1.19A 6b3aA-3emvA:
undetectable
6b3aA-3emvA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)
3emv URIDINE
PHOSPHORYLASE,
PUTATIVE

(Plasmodium
vivax)
4 / 6 GLU A 185
ARG A  89
PHE A 204
VAL A 182
None
SO4  A 254 (-3.2A)
None
None
1.32A 6fgdA-3emvA:
3.6
6fgdA-3emvA:
20.33