SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3en0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		4 / 7 PHE A  60
SER A  32
PHE A  28
ALA A  37
 None
 1.14A 1fxvA-3en0A:
undetectable
1fxvB-3en0A:
undetectable		 1fxvA-3en0A:
22.26
1fxvB-3en0A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 ILE A 169
LEU A 195
GLY A 198
SER A 222
LEU A 250
 None
 1.28A 1kyvA-3en0A:
2.0
1kyvB-3en0A:
undetectable		 1kyvA-3en0A:
21.31
1kyvB-3en0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 169
LEU A 195
GLY A 198
SER A 222
LEU A 250
 None
 1.25A 2a58A-3en0A:
undetectable
2a58B-3en0A:
2.0		 2a58A-3en0A:
21.31
2a58B-3en0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 169
LEU A 195
GLY A 198
SER A 222
LEU A 250
 None
 1.25A 2a58B-3en0A:
2.0
2a58C-3en0A:
undetectable		 2a58B-3en0A:
21.31
2a58C-3en0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 169
LEU A 195
GLY A 198
SER A 222
LEU A 250
 None
 1.25A 2a58D-3en0A:
undetectable
2a58E-3en0A:
undetectable		 2a58D-3en0A:
21.31
2a58E-3en0A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.15A 2f16H-3en0A:
undetectable
2f16I-3en0A:
undetectable		 2f16H-3en0A:
23.38
2f16I-3en0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.14A 2f16V-3en0A:
undetectable
2f16W-3en0A:
undetectable		 2f16V-3en0A:
23.38
2f16W-3en0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 9 LEU A 194
LEU A 195
ILE A 169
LEU A 184
ILE A 188
 None
 1.24A 2f7aB-3en0A:
undetectable		 2f7aB-3en0A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 ALA A 205
ILE A 169
ILE A 199
ALA A 135
VAL A 166
 None
 1.09A 2qhfA-3en0A:
undetectable		 2qhfA-3en0A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 196
ILE A 143
ASP A 225
LEU A 185
LEU A 245
 None
 0.96A 2yqzA-3en0A:
undetectable		 2yqzA-3en0A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 ALA A 136
GLN A 173
ILE A 143
ARG A 183
 None
SO4  A 272 (-3.5A)
None
SO4  A 272 (-3.0A)
 1.24A 2z0aA-3en0A:
undetectable		 2z0aA-3en0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 134
SER A 132
PHE A  95
ILE A  42
ASP A 100
 None
 1.32A 3iv6B-3en0A:
3.4		 3iv6B-3en0A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 126
GLY A  93
ALA A 129
ILE A  38
ALA A  37
 None
 0.96A 3jb1A-3en0A:
undetectable		 3jb1A-3en0A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		4 / 5 ASN A 240
ALA A 155
ALA A 239
ARG A 154
 None
 1.29A 3kp2B-3en0A:
undetectable		 3kp2B-3en0A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.14A 3mg0H-3en0A:
undetectable
3mg0I-3en0A:
undetectable		 3mg0H-3en0A:
23.38
3mg0I-3en0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 11 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.12A 3mg0V-3en0A:
undetectable
3mg0W-3en0A:
undetectable		 3mg0V-3en0A:
23.38
3mg0W-3en0A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 10 LEU A 104
ALA A 136
ILE A 143
GLY A  13
ILE A  12
 None
 0.94A 3ogqA-3en0A:
undetectable		 3ogqA-3en0A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 172
ARG A 180
ASP A 158
 None
SO4  A 272 (-4.5A)
None
 0.88A 4fp9D-3en0A:
2.3		 4fp9D-3en0A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		6 / 12 TYR A  56
ILE A  52
GLY A 134
GLY A  98
ILE A  12
ILE A  11
 None
 1.39A 4iv0B-3en0A:
3.9		 4iv0B-3en0A:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		6 / 12 TYR A  56
ILE A  52
GLY A 134
GLY A  98
ILE A  12
ILE A  11
 None
 1.40A 4mwzA-3en0A:
3.9		 4mwzA-3en0A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		6 / 12 TYR A  56
ILE A  52
GLY A 134
GLY A  98
ILE A  12
ILE A  11
 None
 1.41A 4mwzB-3en0A:
undetectable		 4mwzB-3en0A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 130
ILE A  24
LEU A  25
THR A 131
GLY A  14
 None
 1.01A 5d4uC-3en0A:
3.4		 5d4uC-3en0A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 130
ILE A  24
LEU A  25
THR A 131
GLY A  14
 None
 0.99A 5d4uD-3en0A:
3.5		 5d4uD-3en0A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.12A 5l5fH-3en0A:
undetectable
5l5fI-3en0A:
undetectable		 5l5fH-3en0A:
24.59
5l5fI-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.13A 5l5fV-3en0A:
undetectable
5l5fW-3en0A:
undetectable		 5l5fV-3en0A:
24.59
5l5fW-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.14A 5l5zH-3en0A:
undetectable
5l5zI-3en0A:
undetectable		 5l5zH-3en0A:
24.59
5l5zI-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.16A 5l5zV-3en0A:
undetectable
5l5zW-3en0A:
undetectable		 5l5zV-3en0A:
24.59
5l5zW-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.12A 5l66H-3en0A:
undetectable
5l66I-3en0A:
undetectable		 5l66H-3en0A:
24.59
5l66I-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A  92
SER A 127
GLN A   6
ALA A  37
GLY A  33
 None
 1.11A 5l66V-3en0A:
undetectable
5l66W-3en0A:
undetectable		 5l66V-3en0A:
24.59
5l66W-3en0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 196
PRO A 192
ALA A 226
VAL A 166
PHE A 207
 None
 1.25A 5x6yA-3en0A:
undetectable		 5x6yA-3en0A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 172
ARG A 180
ASP A 158
 None
SO4  A 272 (-4.5A)
None
 0.88A 5zvgB-3en0A:
undetectable		 5zvgB-3en0A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 184
PHE A 207
VAL A 166
VAL A 213
LEU A 248
 None
 1.19A 6djzA-3en0A:
undetectable		 6djzA-3en0A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3en0 CYANOPHYCINASE
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A  12
GLY A  14
ILE A 216
ASP A  17
ILE A  24
 None
 0.97A 6emuA-3en0A:
undetectable		 6emuA-3en0A:
26.67