SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3en8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 6 SER A  93
THR A  78
PHE A  97
GLU A 105
 None
 1.17A 1icuC-3en8A:
undetectable
1icuD-3en8A:
undetectable		 1icuC-3en8A:
19.53
1icuD-3en8A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 4 ARG A  54
ALA A  18
SER A  17
TYR A  80
 None
 1.15A 1j36A-3en8A:
0.0		 1j36A-3en8A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 4 ARG A  54
ALA A  18
SER A  17
TYR A  80
 None
 1.16A 1j36B-3en8A:
undetectable		 1j36B-3en8A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 7 GLU A  25
TYR A  37
TYR A  80
PHE A  64
 None
PG4  A 131 ( 4.1A)
None
None
 1.16A 3ku9B-3en8A:
undetectable		 3ku9B-3en8A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 8 ARG A  47
LEU A  50
ARG A  54
GLU A  25
 None
 1.33A 3zmdA-3en8A:
undetectable
3zmdB-3en8A:
undetectable		 3zmdA-3en8A:
18.18
3zmdB-3en8A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		4 / 6 ARG A  54
GLY A  59
GLU A  25
SER A  17
 None
 1.01A 5ny7A-3en8A:
undetectable		 5ny7A-3en8A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		3 / 3 SER A  17
HIS A  13
TYR A  29
 None
 0.91A 5y2tA-3en8A:
undetectable		 5y2tA-3en8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN
(Paraburkholderia
xenovorans) 		3 / 3 HIS A 104
ARG A  43
ILE A  34
 ACT  A 129 ( 4.5A)
None
ACT  A 129 (-4.3A)
 0.64A 6fgdA-3en8A:
undetectable		 6fgdA-3en8A:
13.91