SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3enh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		4 / 7 ILE C 142
ARG C 123
PHE C 126
ILE C 122
 None
 0.71A 2q6hA-3enhC:
undetectable		 2q6hA-3enhC:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		3 / 3 HIS C  40
GLY C  68
ILE C 142
 None
 0.49A 4k50A-3enhC:
undetectable		 4k50A-3enhC:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		3 / 3 HIS C  40
GLY C  68
ILE C 142
 None
 0.47A 4k50I-3enhC:
undetectable		 4k50I-3enhC:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		4 / 5 ARG C  12
ASP C  33
GLU C 113
VAL C 135
 None
 1.33A 4nkvB-3enhC:
undetectable		 4nkvB-3enhC:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		4 / 7 VAL C 138
ILE C 114
CYH C  87
PHE C 126
 None
 0.96A 5hieC-3enhC:
undetectable		 5hieC-3enhC:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3enh UNCHARACTERIZED
PROTEIN MJ0187
(Methanocaldococc
us
jannaschii) 		5 / 12 ILE C 122
PHE C 126
ILE C 125
LEU C 121
VAL C 138
 None
 0.93A 5km9B-3enhC:
undetectable		 5km9B-3enhC:
21.15