SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IBG_H_OBNH1_2 (IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN) IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN))	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	4 / 7	SER A 117 SER A 220 ARG A 221 LEU A 207	None BCL A 371 ( 3.8A) None None	1.08A	1ibgL-3eniA: undetectable	1ibgL-3eniA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N2X_A_SAMA401_0 (S-ADENOSYL-METHYLTRA NSFERASE MRAW)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	5 / 12	GLY A 116 GLU A 115 GLY A 99 ASP A 146 ASN A 120	BCL A 376 ( 4.0A) None None None None	1.24A	1n2xA-3eniA: undetectable	1n2xA-3eniA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q8J_B_C2FB802_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	5 / 12	GLY A 355 ASP A 233 SER A 236 ILE A 235 GLY A 196	None BCL A 375 ( 4.6A) None None None	1.16A	1q8jB-3eniA: undetectable	1q8jB-3eniA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9A_B_BEZB307_0 (CHLOROCATECHOL 1,2-DIOXYGENASE)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	5 / 12	LEU A 241 ASP A 233 ILE A 292 HIS A 226 GLN A 197	BCL A 375 (-3.7A) BCL A 375 ( 4.6A) BCL A 377 ( 4.8A) BCL A 376 (-3.4A) BCL A 377 (-3.1A)	1.24A	1s9aB-3eniA: undetectable	1s9aB-3eniA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VUF_B_FUAB2002_1 (SERUM ALBUMIN)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	4 / 9	ALA A 345 VAL A 348 CYH A 352 LYS A 353	None BCL A 374 ( 4.1A) BCL A 373 ( 3.8A) None	0.50A	2vufB-3eniA: undetectable	2vufB-3eniA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1200_1 (SERUM ALBUMIN)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	4 / 5	ILE A 235 HIS A 226 TYR A 123 ARG A 198	None BCL A 376 (-3.4A) BCL A 378 (-4.6A) None	1.25A	3b9mA-3eniA: undetectable	3b9mA-3eniA: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	3eni	BACTERIOCHLOROPHYLL A PROTEIN (Chlorobaculum tepidum)	3 / 3	LEU A 294 GLY A 298 PHE A 306	None None BCL A 373 ( 3.8A)	0.60A	6exiC-3eniA: undetectable	6exiC-3eniA: 13.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IBG_H_OBNH1_2","IGG2B-KAPPA 40-50 FAB (HEAVY CHAIN);IGG2B-KAPPA 40-50 FAB (LIGHT CHAIN)","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",4,"SER A 117;SER A 220;ARG A 221;LEU A 207","None;BCL A 371 ( 3.8A);None;None","1.08A","1ibgL-3eniA:undetectable","1ibgL-3eniA:18.57"],["1N2X_A_SAMA401_0","S-ADENOSYL-METHYLTRANSFERASE MRAW","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",5,"GLY A 116;GLU A 115;GLY A  99;ASP A 146;ASN A 120","BCL A 376 ( 4.0A);None;None;None;None","1.24A","1n2xA-3eniA:undetectable","1n2xA-3eniA:22.76"],["1Q8J_B_C2FB802_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",5,"GLY A 355;ASP A 233;SER A 236;ILE A 235;GLY A 196","None;BCL A 375 ( 4.6A);None;None;None","1.16A","1q8jB-3eniA:undetectable","1q8jB-3eniA:21.69"],["1S9A_B_BEZB307_0","CHLOROCATECHOL 1,2-DIOXYGENASE","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",5,"LEU A 241;ASP A 233;ILE A 292;HIS A 226;GLN A 197","BCL A 375 (-3.7A);BCL A 375 ( 4.6A);BCL A 377 ( 4.8A);BCL A 376 (-3.4A);BCL A 377 (-3.1A)","1.24A","1s9aB-3eniA:undetectable","1s9aB-3eniA:21.23"],["2VUF_B_FUAB2002_1","SERUM ALBUMIN","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",4,"ALA A 345;VAL A 348;CYH A 352;LYS A 353","None;BCL A 374 ( 4.1A);BCL A 373 ( 3.8A);None","0.50A","2vufB-3eniA:undetectable","2vufB-3eniA:19.51"],["3B9M_A_SALA1200_1","SERUM ALBUMIN","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",4,"ILE A 235;HIS A 226;TYR A 123;ARG A 198","None;BCL A 376 (-3.4A);BCL A 378 (-4.6A);None","1.25A","3b9mA-3eniA:undetectable","3b9mA-3eniA:19.51"],["6EXI_C_ADNC502_1","ADENOSYLHOMOCYSTEINASE","3eni","BACTERIOCHLOROPHYLL A PROTEIN","Chlorobaculum tepidum",3,"LEU A 294;GLY A 298;PHE A 306","None;None;BCL A 373 ( 3.8A)","0.60A","6exiC-3eniA:undetectable","6exiC-3eniA:13.91"]]