SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3enp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3enp TP53RK-BINDING
PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  27
LEU A  29
ARG A  30
ILE A 105
ALA A  33
 None
 1.02A 3gwvA-3enpA:
undetectable		 3gwvA-3enpA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3enp TP53RK-BINDING
PROTEIN
(Homo
sapiens) 		3 / 3 PHE A  96
VAL A  47
GLU A 144
 None
 0.59A 4fvqA-3enpA:
undetectable		 4fvqA-3enpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3enp TP53RK-BINDING
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 161
ASP A 163
ILE A 166
ILE A 158
VAL A  49
 None
 0.92A 5twjD-3enpA:
undetectable		 5twjD-3enpA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3enp TP53RK-BINDING
PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 165
LEU A 162
MET A 140
THR A  46
 None
 0.85A 5xdqN-3enpA:
undetectable
5xdqW-3enpA:
undetectable		 5xdqN-3enpA:
16.92
5xdqW-3enpA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3enp TP53RK-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A 165
LEU A 162
MET A 140
THR A  46
 None
 0.94A 6nmfN-3enpA:
undetectable
6nmfW-3enpA:
undetectable		 6nmfN-3enpA:
16.92
6nmfW-3enpA:
15.06