SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3enq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 9 LEU A  63
ILE A  65
LEU A  15
VAL A  24
ALA A  49
 None
 1.19A 1e7aA-3enqA:
undetectable		 1e7aA-3enqA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 7 GLU A 103
THR A  31
VAL A  32
ALA A  98
 None
 1.02A 1fo4B-3enqA:
undetectable		 1fo4B-3enqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 ILE A 105
THR A 162
ALA A  99
ILE A 136
THR A 194
 None
 0.93A 2rlcA-3enqA:
undetectable		 2rlcA-3enqA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 9 PHE A  35
VAL A  32
GLY A  82
TYR A  79
GLY A  27
 None
 1.29A 3csjB-3enqA:
undetectable		 3csjB-3enqA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 GLU A 103
GLY A  97
VAL A 192
GLY A 196
PHE A 129
 None
 1.29A 3k13A-3enqA:
undetectable		 3k13A-3enqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		6 / 11 ILE A  36
SER A  56
ALA A  14
VAL A  24
VAL A  26
GLY A  27
 None
 1.31A 3kw4A-3enqA:
undetectable		 3kw4A-3enqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 7 ALA A  14
VAL A  24
VAL A  18
LEU A  15
 None
 0.55A 3o14A-3enqA:
undetectable		 3o14A-3enqA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 ILE A  86
ASP A 170
ILE A 168
ASP A  84
PHE A 129
 None
 1.45A 3phaB-3enqA:
undetectable		 3phaB-3enqA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 ILE A  86
ASP A 170
ILE A 168
ASP A  84
PHE A 129
 None
 1.46A 3phaD-3enqA:
undetectable		 3phaD-3enqA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		3 / 3 SER A  30
ASP A  84
ASP A 170
 None
 0.67A 3uj7A-3enqA:
2.1		 3uj7A-3enqA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 ALA A  83
ASP A 170
ILE A 168
ASP A  84
PHE A 129
 None
 1.50A 3weoA-3enqA:
undetectable		 3weoA-3enqA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 ASP A 170
ILE A 168
LEU A 100
ASP A  84
PHE A 129
 None
 1.48A 4b9zA-3enqA:
undetectable		 4b9zA-3enqA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 VAL A 195
LEU A 169
VAL A 135
ALA A 144
LEU A 150
 None
 1.12A 4i1rA-3enqA:
undetectable		 4i1rA-3enqA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 6 ILE A  78
ILE A  46
PHE A  35
LEU A  15
 None
 0.90A 4m51A-3enqA:
undetectable		 4m51A-3enqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 9 ASP A 170
TYR A 172
GLY A  96
PHE A 129
GLY A 127
 None
 1.33A 4mmfA-3enqA:
undetectable		 4mmfA-3enqA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 9 ASP A 170
TYR A 172
GLY A  96
PHE A 129
GLY A 127
 None
 1.38A 4mmfB-3enqA:
undetectable		 4mmfB-3enqA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		3 / 3 SER A  30
ASP A  84
ASP A 170
 None
 0.71A 4mwzA-3enqA:
2.4		 4mwzA-3enqA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 VAL A 106
VAL A  73
ILE A 109
ILE A  23
GLY A  48
 None
 1.01A 4y8wC-3enqA:
undetectable		 4y8wC-3enqA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 GLY A 196
GLY A  95
GLY A  96
ALA A 199
LEU A 126
 None
 0.84A 5c0oF-3enqA:
3.2		 5c0oF-3enqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 8 GLY A 196
ARG A 157
ASP A 170
ASP A  84
 None
 0.98A 5vlmB-3enqA:
undetectable		 5vlmB-3enqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 8 ILE A 168
ARG A 157
VAL A 171
ASP A  84
 None
 1.01A 5vlmF-3enqA:
undetectable		 5vlmF-3enqA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 8 LEU A 169
VAL A 133
VAL A 135
ILE A 189
 None
 0.78A 5y9mA-3enqA:
undetectable		 5y9mA-3enqA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		4 / 8 LEU A 169
VAL A 133
VAL A 135
ILE A 189
 None
 0.73A 5y9mX-3enqA:
undetectable		 5y9mX-3enqA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 3enq RIBOSE-5-PHOSPHATE
ISOMERASE A
(Vibrio
vulnificus) 		5 / 12 GLY A  40
SER A  43
ALA A  49
VAL A  50
SER A  51
 None
 0.97A 6c2mC-3enqA:
undetectable		 6c2mC-3enqA:
19.91