SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 3eo2 NEUROEPITHELIAL
CELL-TRANSFORMING
GENE 1 PROTEIN
(Homo
sapiens) 		5 / 10 LEU A 228
LEU A 260
ALA A 262
LEU A 350
VAL A 349
 None
 0.98A 2bxgB-3eo2A:
undetectable		 2bxgB-3eo2A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 3eo2 NEUROEPITHELIAL
CELL-TRANSFORMING
GENE 1 PROTEIN
(Homo
sapiens) 		3 / 3 LEU A 321
MET A 182
ASP A 309
 None
 0.81A 4j7xB-3eo2A:
undetectable		 4j7xB-3eo2A:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3eo2 NEUROEPITHELIAL
CELL-TRANSFORMING
GENE 1 PROTEIN
(Homo
sapiens) 		4 / 4 THR A 245
ARG A 175
GLU A 172
VAL A 246
 None
 1.47A 4odoC-3eo2A:
undetectable		 4odoC-3eo2A:
18.85