SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eo4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 449
GLY A 446
GLY A 436
GLY A 417
ILE A 374
 None
MES  A   2 (-3.7A)
None
None
None
 0.95A 2wa2B-3eo4A:
undetectable		 2wa2B-3eo4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		3 / 3 PRO A 384
LEU A 385
GLN A 381
 None
 0.57A 3hznG-3eo4A:
undetectable
3hznH-3eo4A:
undetectable		 3hznG-3eo4A:
20.89
3hznH-3eo4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 449
GLY A 446
GLY A 436
GLY A 417
ILE A 374
 None
MES  A   2 (-3.7A)
None
None
None
 0.83A 4ctkC-3eo4A:
undetectable		 4ctkC-3eo4A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A 374
ARG A 369
GLY A 417
VAL A 419
 None
MES  A   8 (-4.2A)
None
None
 1.01A 4oltA-3eo4A:
undetectable		 4oltA-3eo4A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A 374
ARG A 369
GLY A 417
VAL A 419
 None
MES  A   8 (-4.2A)
None
None
 0.96A 4oltB-3eo4A:
undetectable		 4oltB-3eo4A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_2
(TUBULIN ALPHA-1B
CHAIN)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		5 / 7 VAL A 419
ASN A 420
ILE A 431
VAL A 453
ILE A 354
 None
MES  A   8 (-3.4A)
None
None
None
 1.46A 5bmvC-3eo4A:
undetectable		 5bmvC-3eo4A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3eo4 UNCHARACTERIZED
PROTEIN MJ1062
(Methanocaldococc
us
jannaschii) 		5 / 12 SER A 449
GLY A 446
GLY A 436
GLY A 417
ILE A 374
 None
MES  A   2 (-3.7A)
None
None
None
 0.83A 5ec8A-3eo4A:
undetectable		 5ec8A-3eo4A:
19.72