SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		4 / 8 SER A  35
LEU A  31
LEU A 102
ARG A  58
 None
 0.92A 2j2pA-3eo6A:
undetectable
2j2pB-3eo6A:
undetectable		 2j2pA-3eo6A:
20.09
2j2pB-3eo6A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		4 / 8 VAL A  59
MET A  83
ILE A  57
GLU A  97
 None
 0.99A 4a97D-3eo6A:
undetectable		 4a97D-3eo6A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		4 / 8 VAL A  59
MET A  83
ILE A  57
GLU A  97
 None
 1.06A 4a97G-3eo6A:
undetectable		 4a97G-3eo6A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		4 / 8 VAL A  59
MET A  83
ILE A  57
GLU A  97
 None
 1.00A 4a97I-3eo6A:
undetectable		 4a97I-3eo6A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		4 / 5 TYR A 101
LEU A  42
TYR A  47
LEU A  49
 None
 1.28A 4em2A-3eo6A:
undetectable		 4em2A-3eo6A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		5 / 10 GLY A  22
SER A  19
LEU A  20
LEU A  42
ARG A  24
 None
 1.38A 5hwkA-3eo6A:
undetectable		 5hwkA-3eo6A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3eo6 PROTEIN OF UNKNOWN
FUNCTION (DUF1255)
(Acidithiobacillu
s
ferrooxidans) 		5 / 10 GLY A  22
SER A  19
LEU A  20
LEU A  42
ARG A  24
 None
 1.37A 5hwkB-3eo6A:
undetectable		 5hwkB-3eo6A:
19.11