SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eo9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_B_ADNB438_2 (ADENOSYLHOMOCYSTEINA SE)	3eo9	EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	3 / 3	THR H 118 GLU H 156 HIS H 208	None	0.78A	3g1uB-3eo9H: undetectable	3g1uB-3eo9H: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA312_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3eo9	EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	3 / 3	ARG H 98 HIS H 32 TYR H 110	None	1.34A	4fu9A-3eo9H: undetectable	4fu9A-3eo9H: 23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4M7K_H_ACTH302_0 (10H10 HEAVY CHAIN)	3eo9	EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	4 / 5	VAL H 2 TYR H 27 ARG H 98 TYR H 110	None	0.44A	4m7kH-3eo9H: 21.7	4m7kH-3eo9H: 75.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMD_A_YMZA3801_1 (60S RIBOSOMAL PROTEIN L28 28S RIBOSOMAL RNA 60S RIBOSOMAL PROTEIN L4)	3eo9	EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN (Homo sapiens)	4 / 6	ASN H 77 ALA H 24 PRO H 53 TYR H 27	None	1.05A	5umd2-3eo9H: undetectable 5umdF-3eo9H: undetectable	5umd2-3eo9H: 20.43 5umdF-3eo9H: 17.14

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3G1U_B_ADNB438_2","ADENOSYLHOMOCYSTEINASE","3eo9","EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN","Homo sapiens",3,"THR H 118;GLU H 156;HIS H 208","None","0.78A","3g1uB-3eo9H:undetectable","3g1uB-3eo9H:20.40"],["4FU9_A_ACTA312_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3eo9","EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN","Homo sapiens",3,"ARG H  98;HIS H  32;TYR H 110","None","1.34A","4fu9A-3eo9H:undetectable","4fu9A-3eo9H:23.62"],["4M7K_H_ACTH302_0","10H10 HEAVY CHAIN","3eo9","EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN","Homo sapiens",4,"VAL H   2;TYR H  27;ARG H  98;TYR H 110","None","0.44A","4m7kH-3eo9H:21.7","4m7kH-3eo9H:75.34"],["5UMD_A_YMZA3801_1","60S RIBOSOMAL PROTEIN L28;28S RIBOSOMAL RNA;60S RIBOSOMAL PROTEIN L4","3eo9","EFALIZUMAB FAB FRAGMENT, HEAVY CHAIN","Homo sapiens",4,"ASN H  77;ALA H  24;PRO H  53;TYR H  27","None","1.05A","5umd2-3eo9H:undetectable;5umdF-3eo9H:undetectable","5umd2-3eo9H:20.43;5umdF-3eo9H:17.14"]]