SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3eod PROTEIN HNR
(Escherichia
coli) 		5 / 12 ILE A  12
LEU A   5
PHE A  27
LEU A 116
ILE A  56
 None
 1.02A 1drbB-3eodA:
undetectable		 1drbB-3eodA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3eod PROTEIN HNR
(Escherichia
coli) 		5 / 12 ILE A  12
LEU A   5
PHE A  27
LEU A 116
ILE A  56
 None
 1.12A 1rb2B-3eodA:
undetectable		 1rb2B-3eodA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 3eod PROTEIN HNR
(Escherichia
coli) 		5 / 12 ILE A  12
LEU A   5
PHE A  27
LEU A 116
ILE A  56
 None
 1.12A 1re7B-3eodA:
undetectable		 1re7B-3eodA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 3eod PROTEIN HNR
(Escherichia
coli) 		4 / 6 PRO A  52
LEU A  23
ILE A  12
SER A  28
 None
 1.12A 1sbrA-3eodA:
undetectable
1sbrB-3eodA:
undetectable		 1sbrA-3eodA:
21.21
1sbrB-3eodA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 3eod PROTEIN HNR
(Escherichia
coli) 		4 / 6 LEU A 124
PHE A 121
ALA A 122
LEU A  54
 None
 0.84A 1ukbA-3eodA:
5.1		 1ukbA-3eodA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3eod PROTEIN HNR
(Escherichia
coli) 		4 / 8 ASP A 104
LEU A 116
LEU A  83
SER A  86
 None
 0.88A 3lm8A-3eodA:
2.3
3lm8C-3eodA:
undetectable		 3lm8A-3eodA:
22.33
3lm8C-3eodA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3eod PROTEIN HNR
(Escherichia
coli) 		5 / 12 PRO A  81
ARG A  74
ALA A  97
GLY A  66
LEU A  67
 None
 1.10A 4oaeA-3eodA:
undetectable		 4oaeA-3eodA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3eod PROTEIN HNR
(Escherichia
coli) 		5 / 12 LEU A  83
PHE A 121
PRO A   4
GLY A  31
LEU A  30
 None
 1.10A 5ogcB-3eodA:
4.3		 5ogcB-3eodA:
15.33