SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eoj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 12 GLY A 116
GLU A 115
GLY A  99
ASP A 146
ASN A 120
 BCL  A 376 ( 4.1A)
None
EDO  A 385 ( 4.0A)
None
None
 1.32A 1n2xA-3eojA:
undetectable		 1n2xA-3eojA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 7 ASP A 154
ASN A 155
PHE A 108
SER A 111
 NA  A1232 ( 4.9A)
None
BCL  A 371 (-4.2A)
EDO  A 383 ( 4.3A)
 1.43A 1rqpB-3eojA:
undetectable		 1rqpB-3eojA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 7 LEU A 292
ARG A 125
GLU A 361
ARG A 286
 EDO  A 389 ( 4.4A)
None
None
None
 1.08A 2jn3A-3eojA:
undetectable		 2jn3A-3eojA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 9 ALA A 346
VAL A 349
CYH A 353
LYS A 354
 None
BCL  A 374 ( 4.0A)
BCL  A 373 ( 3.8A)
None
 0.52A 2vufB-3eojA:
2.3		 2vufB-3eojA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 5 ILE A 236
HIS A 227
TYR A 123
ARG A 199
 None
BCL  A 376 (-3.5A)
BCL  A 378 (-4.6A)
EDO  A 379 ( 3.5A)
 1.23A 3b9mA-3eojA:
undetectable		 3b9mA-3eojA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 12 ALA A 192
ILE A 293
PHE A 185
SER A 235
ILE A 200
 BCL  A 377 (-3.6A)
None
BCL  A 377 ( 4.2A)
BCL  A 376 ( 3.9A)
EDO  A 381 (-4.8A)
 1.12A 3clbB-3eojA:
undetectable		 3clbB-3eojA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 7 SER A 111
LEU A 153
ASP A 154
LYS A 215
 EDO  A 383 ( 4.3A)
None
NA  A1232 ( 4.9A)
None
 1.28A 3lslA-3eojA:
undetectable
3lslD-3eojA:
undetectable		 3lslA-3eojA:
20.97
3lslD-3eojA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		3 / 3 ASP A 146
GLU A  90
SER A 207
 None
 0.55A 3p2kA-3eojA:
undetectable		 3p2kA-3eojA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 10 SER A  24
ALA A 252
LEU A 273
GLY A 275
ALA A  33
 None
BCL  A 376 ( 3.8A)
BCL  A 376 ( 4.2A)
BCL  A 375 ( 3.8A)
BCL  A 373 (-3.5A)
 1.47A 4fe1A-3eojA:
undetectable
4fe1J-3eojA:
undetectable		 4fe1A-3eojA:
19.24
4fe1J-3eojA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 9 SER A  24
ALA A 252
LEU A 273
GLY A 275
ALA A  33
 None
BCL  A 376 ( 3.8A)
BCL  A 376 ( 4.2A)
BCL  A 375 ( 3.8A)
BCL  A 373 (-3.5A)
 1.20A 4l6va-3eojA:
undetectable
4l6vf-3eojA:
undetectable		 4l6va-3eojA:
17.51
4l6vf-3eojA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 9 TYR A 364
ILE A 287
ILE A 315
VAL A 276
ILE A  18
 None
BCL  A 374 ( 4.3A)
None
BCL  A 375 ( 4.5A)
None
 1.48A 5mvnB-3eojA:
2.6		 5mvnB-3eojA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		5 / 10 TYR A 364
ILE A 287
ILE A 315
VAL A 276
ILE A  18
 None
BCL  A 374 ( 4.3A)
None
BCL  A 375 ( 4.5A)
None
 1.47A 5mvnD-3eojA:
2.6		 5mvnD-3eojA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		3 / 3 ARG A 286
PRO A 134
TYR A 325
 None
 0.96A 5tzoB-3eojA:
undetectable		 5tzoB-3eojA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA902_0
(PROTEIN ARGONAUTE-2)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 4 VAL A  63
ALA A  97
PHE A 243
PHE A  66
 EDO  A 392 (-4.7A)
BCL  A 376 (-3.6A)
BCL  A 375 (-4.4A)
BCL  A 375 (-4.6A)
 1.41A 6cbdA-3eojA:
0.0		 6cbdA-3eojA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		3 / 3 LEU A 295
GLY A 299
PHE A 307
 None
None
BCL  A 373 ( 3.6A)
 0.60A 6exiC-3eojA:
undetectable		 6exiC-3eojA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 3eoj BACTERIOCHLOROPHYLL
A PROTEIN
(Prosthecochloris
aestuarii) 		4 / 8 VAL A 232
HIS A 290
ASN A 289
GLU A 241
 EDO  A 389 ( 4.5A)
BCL  A 374 (-3.3A)
EDO  A 391 ( 4.4A)
BCL  A 375 ( 4.0A)
 1.07A 6gneB-3eojA:
undetectable		 6gneB-3eojA:
21.40