SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eoo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 236
LEU A  86
VAL A  17
LYS A  12
ALA A  16
 None
 1.09A 1sa1A-3eooA:
2.7
1sa1B-3eooA:
undetectable		 1sa1A-3eooA:
21.06
1sa1B-3eooA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		5 / 12 LEU A 236
LEU A  86
VAL A  17
LYS A  12
ALA A  16
 None
 1.11A 1sa1C-3eooA:
undetectable
1sa1D-3eooA:
undetectable		 1sa1C-3eooA:
21.06
1sa1D-3eooA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		3 / 3 SER A  65
ASP A  90
ASP A  73
 None
 0.80A 3iv6A-3eooA:
undetectable		 3iv6A-3eooA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		3 / 3 GLU A 285
LEU A 288
ASP A 289
 None
 0.41A 3ko0T-3eooA:
undetectable		 3ko0T-3eooA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  74
THR A 102
ILE A 103
ARG A 150
ILE A  89
 None
 1.11A 5e8qA-3eooA:
undetectable		 5e8qA-3eooA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		5 / 12 ALA A  15
ALA A 113
PHE A 155
GLY A  10
SER A   8
 None
 1.42A 5jglA-3eooA:
undetectable		 5jglA-3eooA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		4 / 8 ARG A 160
GLU A 117
GLY A  63
ASP A  61
 None
 1.03A 5kf8A-3eooA:
undetectable		 5kf8A-3eooA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		4 / 8 ARG A 160
GLU A 117
GLY A  63
ASP A  61
 None
 1.10A 5kgpA-3eooA:
undetectable		 5kgpA-3eooA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3eoo METHYLISOCITRATE
LYASE
(Burkholderia
pseudomallei) 		4 / 8 ARG A 160
GLU A 117
GLY A  63
ASP A  61
 None
 1.14A 5kgpB-3eooA:
undetectable		 5kgpB-3eooA:
21.53