SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3eop THYMOCYTE NUCLEAR
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A 154
LYS A 157
ARG A  99
 None
 1.07A 1ra8A-3eopA:
undetectable		 1ra8A-3eopA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3eop THYMOCYTE NUCLEAR
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A  91
LEU A 102
VAL A 130
 None
 0.69A 4jecB-3eopA:
undetectable		 4jecB-3eopA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3eop THYMOCYTE NUCLEAR
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 208
LEU A 197
ILE A 173
LEU A 178
LEU A 126
 None
 1.21A 5toaB-3eopA:
undetectable		 5toaB-3eopA:
21.09