SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3epc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 5 ASP 2 135
SER 2 136
ASN 2 166
SER 2 144
 None
 1.49A 1kiaB-3epc2:
undetectable		 1kiaB-3epc2:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 6 ASP 2 135
SER 2 136
ASN 2 166
SER 2 144
 None
 1.47A 1kiaC-3epc2:
undetectable		 1kiaC-3epc2:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3epc PROTEIN VP1
(Enterovirus
C) 		4 / 5 LEU 1 291
TYR 1 286
ARG 1 275
THR 1 290
 None
 1.38A 1nw3A-3epc1:
undetectable		 1nw3A-3epc1:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 3epc PROTEIN VP1
(Enterovirus
C) 		4 / 7 SER 1 255
ILE 1 157
ILE 1 257
THR 1 139
 None
 0.96A 1sbrB-3epc1:
undetectable		 1sbrB-3epc1:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3epc PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		3 / 3 TRP 2 227
THR 1 126
TYR 1 127
 None
 1.28A 2a3aA-3epc2:
undetectable		 2a3aA-3epc2:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3epc PROTEIN VP1
PROTEIN VP2
(Enterovirus
C;
Enterovirus
C) 		3 / 3 ASP 1 285
ASP 2 135
ASN 2 183
 None
 0.80A 2bm9D-3epc1:
undetectable		 2bm9D-3epc1:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 7 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.06A 2ejfA-3epc2:
undetectable		 2ejfA-3epc2:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 7 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.07A 2zgwA-3epc2:
undetectable		 2zgwA-3epc2:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 6 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.09A 2zgwB-3epc2:
undetectable		 2zgwB-3epc2:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 6 GLU 2 259
TYR 2  41
SER 2 217
ASP 2  44
 None
 1.30A 2zvjA-3epc2:
undetectable		 2zvjA-3epc2:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3epc PROTEIN VP1
(Enterovirus
C) 		4 / 5 ILE 1 157
ARG 1 258
MET 1  90
THR 1  91
 None
 1.25A 3abkN-3epc1:
undetectable
3abkW-3epc1:
undetectable		 3abkN-3epc1:
20.11
3abkW-3epc1:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3epc PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		3 / 3 THR 1  45
GLU 1  48
HIS 2 195
 None
 0.81A 3g1uB-3epc1:
undetectable		 3g1uB-3epc1:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B204_1
(PROTEIN S100-A4)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 6 MET 2 130
CYH 2 131
PHE 2 174
PHE 2 157
 None
 1.33A 3m0wB-3epc2:
undetectable
3m0wJ-3epc2:
undetectable		 3m0wB-3epc2:
16.85
3m0wJ-3epc2:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3epc PROTEIN VP2
(Enterovirus
C) 		3 / 3 PRO 2  53
THR 2  54
LEU 2 263
 None
 0.58A 3ttrA-3epc2:
undetectable		 3ttrA-3epc2:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3epc PROTEIN VP2
(Enterovirus
C) 		5 / 11 PHE 2 157
GLY 2 159
LEU 2 232
GLY 2  77
ALA 2  34
 None
 1.12A 4l6v1-3epc2:
undetectable
4l6v6-3epc2:
undetectable		 4l6v1-3epc2:
16.19
4l6v6-3epc2:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3epc PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		4 / 5 TYR 1 279
THR 2 158
THR 2 140
MET 2 141
 None
 1.35A 4mbsB-3epc1:
undetectable		 4mbsB-3epc1:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3epc PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		4 / 6 TYR 1 286
ASN 2 183
LEU 2 187
PHE 2 157
 None
 1.19A 4twdI-3epc1:
undetectable
4twdJ-3epc1:
undetectable		 4twdI-3epc1:
20.00
4twdJ-3epc1:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3epc PROTEIN VP2
(Enterovirus
C) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.51A 4xmfA-3epc2:
undetectable		 4xmfA-3epc2:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3epc PROTEIN VP2
(Enterovirus
C) 		3 / 3 ALA 2 254
TYR 2  64
PRO 2  56
 None
 0.63A 4zdyA-3epc2:
undetectable		 4zdyA-3epc2:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3epc PROTEIN VP2
(Enterovirus
C) 		4 / 4 VAL 2 110
ALA 2 206
ASN 2 203
GLN 2 196
 None
 1.49A 4zgfA-3epc2:
undetectable		 4zgfA-3epc2:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3epc PROTEIN VP2
(Enterovirus
C) 		5 / 10 VAL 2 108
ILE 2 253
LEU 2  86
GLY 2 228
ALA 2 126
 None
 1.00A 5mxbA-3epc2:
undetectable		 5mxbA-3epc2:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 3epc PROTEIN VP1
(Enterovirus
C) 		4 / 7 ILE 1 110
PHE 1 237
LYS 1 113
SER 1 128
 SPH  1   0 (-4.5A)
SPH  1   0 ( 3.1A)
None
None
 1.37A 5nr3A-3epc1:
undetectable		 5nr3A-3epc1:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3epc PROTEIN VP2
(Enterovirus
C) 		5 / 10 VAL 2 124
GLY 2 123
ALA 2 206
ASN 2 199
ASN 2 203
 None
 1.08A 5x6yB-3epc2:
undetectable		 5x6yB-3epc2:
14.02