SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3epf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 6 TRP 2  78
VAL 2  69
ILE 2 248
LEU 2 233
 None
 1.27A 1j96A-3epf2:
undetectable		 1j96A-3epf2:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 8 PRO 2  56
LEU 2  91
GLY 2  90
PRO 2 254
 None
 0.95A 1ya4A-3epf2:
undetectable		 1ya4A-3epf2:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		3 / 3 TRP 2 226
THR 1 126
TYR 1 127
 None
 1.26A 2a3aA-3epf2:
undetectable		 2a3aA-3epf2:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 5 GLY 2  93
PRO 2 268
VAL 2 267
ILE 2 265
 None
 0.97A 2aoiA-3epf2:
undetectable		 2aoiA-3epf2:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		5 / 8 TYR 2 192
ARG 1 272
GLY 2 181
ALA 2 189
ALA 2 186
 None
 1.42A 2ej3C-3epf2:
undetectable		 2ej3C-3epf2:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_A_ADNA2001_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 7 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 0.99A 2ejfA-3epf2:
undetectable		 2ejfA-3epf2:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 7 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 0.97A 2zgwA-3epf2:
undetectable		 2zgwA-3epf2:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 6 GLU 2  55
ALA 2  59
ASN 2  95
ALA 2  60
 None
 1.00A 2zgwB-3epf2:
undetectable		 2zgwB-3epf2:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		3 / 3 THR 1  45
GLU 1  48
HIS 2 194
 None
 0.83A 3g1uB-3epf1:
undetectable		 3g1uB-3epf1:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_B_P77B204_1
(PROTEIN S100-A4)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 6 MET 2 130
CYH 2 131
PHE 2 173
PHE 2 156
 None
 1.35A 3m0wB-3epf2:
undetectable
3m0wJ-3epf2:
undetectable		 3m0wB-3epf2:
16.35
3m0wJ-3epf2:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 3epf PROTEIN VP1
(Enterovirus
C) 		5 / 12 ILE 1  90
ALA 1 241
LEU 1 240
GLY 1 168
PRO 1 167
 None
None
SC4  1 999 ( 4.7A)
None
None
 1.11A 3ozwB-3epf1:
undetectable		 3ozwB-3epf1:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3epf PROTEIN VP2
(Enterovirus
C) 		3 / 3 PRO 2  53
THR 2  54
LEU 2 262
 None
 0.40A 3ttrA-3epf2:
undetectable		 3ttrA-3epf2:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3epf PROTEIN VP1
(Enterovirus
C) 		4 / 8 VAL 1 242
VAL 1 183
TYR 1 185
TYR 1 155
 None
 0.69A 3v81C-3epf1:
undetectable		 3v81C-3epf1:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		5 / 12 PHE 1 208
LEU 2 132
ALA 2 133
ARG 1 272
GLY 1 289
 None
 1.11A 4dm8B-3epf1:
undetectable		 4dm8B-3epf1:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3epf PROTEIN VP2
(Enterovirus
C) 		4 / 6 ASN 2  30
ALA 2  28
THR 2  25
LEU 2  16
 None
 1.05A 4ejgD-3epf2:
undetectable		 4ejgD-3epf2:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C;
Enterovirus
C) 		4 / 8 LEU 2 231
PRO 1 273
VAL 1 277
GLY 2 183
 None
 1.01A 4klrB-3epf2:
undetectable		 4klrB-3epf2:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3epf PROTEIN VP1
(Enterovirus
C) 		4 / 8 VAL 1 242
VAL 1 183
TYR 1 185
TYR 1 155
 None
 0.58A 4puoC-3epf1:
undetectable		 4puoC-3epf1:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3epf PROTEIN VP1
(Enterovirus
C) 		4 / 8 VAL 1 242
VAL 1 183
TYR 1 185
TYR 1 155
 None
 0.61A 4pwdC-3epf1:
undetectable		 4pwdC-3epf1:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3epf PROTEIN VP2
(Enterovirus
C) 		3 / 3 ASP 2  57
LEU 2  18
GLY 2  19
 None
 0.45A 4xmfA-3epf2:
undetectable		 4xmfA-3epf2:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3epf PROTEIN VP2
(Enterovirus
C) 		3 / 3 ALA 2 253
TYR 2  64
PRO 2  56
 None
 0.68A 4zdyA-3epf2:
undetectable		 4zdyA-3epf2:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3epf PROTEIN VP2
(Enterovirus
C) 		5 / 10 VAL 2 108
ILE 2 252
LEU 2  86
GLY 2 227
ALA 2 126
 None
 0.98A 5mxbA-3epf2:
undetectable		 5mxbA-3epf2:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3epf PROTEIN VP1
(Enterovirus
C) 		3 / 3 VAL 1  77
LYS 1 262
MET 1 261
 None
None
SC4  1 999 ( 4.6A)
 0.88A 5nknA-3epf1:
undetectable		 5nknA-3epf1:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3epf PROTEIN VP1
PROTEIN VP2
(Enterovirus
C) 		4 / 8 VAL 1  47
GLU 1  48
GLY 2 123
LEU 2 233
 None
 0.94A 5w3jB-3epf1:
undetectable		 5w3jB-3epf1:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_B_SAMB901_0
(MRNA CAPPING ENZYME
P5)		 3epf PROTEIN VP2
(Enterovirus
C) 		5 / 10 VAL 2 124
GLY 2 123
ALA 2 205
ASN 2 198
ASN 2 202
 None
 1.10A 5x6yB-3epf2:
undetectable		 5x6yB-3epf2:
14.19