SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3epu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		5 / 12 ASP A 134
LEU A 133
GLY A  56
ASP A  86
LEU A 122
 None
 0.93A 2nxeA-3epuA:
undetectable		 2nxeA-3epuA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		5 / 12 ASP A 134
LEU A 133
GLY A  56
ASP A  86
LEU A 122
 None
 1.03A 2nxeB-3epuA:
undetectable		 2nxeB-3epuA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		4 / 7 GLY A  53
PHE A  31
ILE A  33
PHE A  12
 None
 0.95A 2qmzA-3epuA:
undetectable
2qmzB-3epuA:
undetectable		 2qmzA-3epuA:
18.22
2qmzB-3epuA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		5 / 12 ASP A 134
LEU A 133
GLY A  56
ASP A  86
LEU A 122
 None
 1.00A 3cjtC-3epuA:
undetectable		 3cjtC-3epuA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		4 / 5 LEU A  28
ASP A  24
LEU A  40
THR A  44
 None
 1.23A 4wozF-3epuA:
undetectable
4wozH-3epuA:
undetectable		 4wozF-3epuA:
19.14
4wozH-3epuA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 3epu STM2138 VIRULENCE
CHAPERONE
(Salmonella
enterica) 		5 / 12 LEU A  96
GLY A  53
TYR A  37
PHE A  12
LEU A 108
 None
 1.37A 5kklB-3epuA:
undetectable		 5kklB-3epuA:
8.75