SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 271
TYR A 196
ALA A 205
TYR A 207
 None
 1.04A 1dmaB-3eq2A:
undetectable		 1dmaB-3eq2A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3002_1
(SERUM ALBUMIN)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  43
LEU A  39
LEU A  67
ARG A  70
LEU A   9
 None
 1.22A 1hk1A-3eq2A:
0.0		 1hk1A-3eq2A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  25
TYR A  24
VAL A  32
ILE A  10
LEU A 108
 None
 1.33A 1mrqA-3eq2A:
undetectable		 1mrqA-3eq2A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  83
LEU A 114
LEU A  25
ALA A  22
ILE A  10
 None
 1.24A 2bxpA-3eq2A:
undetectable		 2bxpA-3eq2A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 389
PHE A 329
ILE A 274
ASN A 279
 None
 0.73A 2opxA-3eq2A:
3.4		 2opxA-3eq2A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 384
LEU A 339
ARG A 182
GLY A 373
 None
 0.85A 2vdbA-3eq2A:
undetectable		 2vdbA-3eq2A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 4 ASP A 383
ASP A 192
GLY A 213
THR A 268
 None
 1.08A 3tl9B-3eq2A:
undetectable		 3tl9B-3eq2A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 309
ARG A 321
LEU A 251
 None
 1.23A 3v4tE-3eq2A:
undetectable		 3v4tE-3eq2A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  25
GLU A  26
SER A  28
 None
 0.82A 4ccqA-3eq2A:
2.3		 4ccqA-3eq2A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  67
ILE A  68
ARG A  72
 None
 0.67A 4mk4B-3eq2A:
4.5		 4mk4B-3eq2A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 GLU A 178
GLY A 176
GLU A 175
LEU A 331
LEU A 294
 None
 1.25A 4wcxC-3eq2A:
3.4		 4wcxC-3eq2A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 283
SER A 284
GLU A 249
ASP A 319
 None
 1.37A 4xueA-3eq2A:
undetectable		 4xueA-3eq2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 276
PHE A 206
LEU A 389
GLY A 272
LEU A 325
 None
 1.38A 4zbrA-3eq2A:
undetectable		 4zbrA-3eq2A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 4 TYR A 283
SER A 284
GLU A 249
ASP A 319
 None
 1.37A 5lsaA-3eq2A:
1.4		 5lsaA-3eq2A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3eq2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 221
LEU A 224
HIS A 253
THR A 261
 None
 1.39A 6dyoA-3eq2A:
undetectable		 6dyoA-3eq2A:
11.93